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Similac Pro-Sensitive™*

Gentle nutrition for fussiness, gas, or mild spit-up, with added 2’-FL HMO prebiotic for immune support


Similac is the first infant formula brand with 2’-FL Human Milk Oligosaccharide (HMO), an immune-nourishing prebiotic that circulates throughout the body. Similac with 2’-FL HMO helps strengthen baby’s immune system to be more like the breastfed infant’s than ever before.


2’-FL HMO facts:

  • Naturally abundant in most breast milk
  • Backed by more than 15 years of extensive research
  • Adds another layer to Similac’s already proven immune support

Similac is the first leading infant formula brand with no artificial growth hormones.§ Similac dairy ingredients come from cows that have not been treated with artificial growth hormones.

Similac Pro-Sensitive is non-GMO|| and has OptiGRO™, our unique blend of DHA, Lutein, and Vitamin E, to help support your baby’s overall growth, and brain and eye development. Trust Similac Pro-Sensitive to provide a strong start for your baby’s developing immune system.

* Not for infants or children with galactosemia.
Due to lactose sensitivity.
Not from human milk.
§ No significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows.
|| Ingredients not genetically engineered.

Similac Pro-Sensitive™ Milk-Based Infant Formula Container

Available In:

Similac Pro Sensitive Formula Powder Can 29.8-oz Powder

Similac Pro-Sensitive™ Milk-Based Infant Formula Tub 1.41-lb Powder

1 QT Ready to Feed Similac Pro Sensitive Formula Bottle 1-qt Ready to Feed

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

1.41 lb. Similac Pro-Sensitive™ milk-based powder formula
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Similac Pro-Sensitive Reviews

Rated 5 out of 5 by from Fantastic! Stir don’t shake formula Great formula! My daughter would cry for hours at night and we were going through gas drops and different types/brands of formula but nothing was working. We thought maybe she had an issue with lactose so we were about to head down the soy formula path when we read about Similac Pro in one of our 2 am desperate google searches. We tried Similac-Pro when she was about 1 month old. Immediate results - she stopped getting gassy and no more hours of crying/fussiness. She is now 9 months old. We purchase ours at Costco. **Special note: STIR the formula and water together, do not shake like you would with other formulas**
Date published: 2018-09-23
Rated 4 out of 5 by from Works wonders for my newborn My newborn girl has a lactose sensitivity and this formula works great for her! Perfect for when Mama just can’t get enough milk in.
Date published: 2018-09-20
Rated 5 out of 5 by from Works great for my daughter After my daughter was born we introduced Similac Pro-Advance. She did well on it for a few weeks but began to become very fussy and gassy and lots of spit up and would cry for hours and not sleep at all. I began to switch over to Similiac Pro- Sensitive and she is a different baby! Not so much gas, sleeps great, no spit up and she’s finally pooping!! Only downside is I just opened a big can of pro - advance and now I can’t use it but that’s ok if it means my baby won’t be so fussy and in pain anymore !
Date published: 2018-09-18
Rated 5 out of 5 by from Works great Works great so far. Both the prepared and powdered formula.
Date published: 2018-09-13
Rated 4 out of 5 by from Worked great for our baby girl! Thankful we started our baby girl out on the Pro Sensitive right away! All of our kiddos have had atomach issues when they were small so we didnt want to chance it one more time with regular formula. Although the formula is quite expensive, it has worked wonders for our girl. The only downside that I have found ( other than being expensive ) is that when shaken to make the bottle, there is a TON of bubbles/froth. Not sure how to fix that? All in all, I would 100% recommend this to other mamas!
Date published: 2018-09-13
Rated 3 out of 5 by from Good but... I don’t understand why it’s so foamy no matter what i do when i mix it it foams. Might be switching formulas based on this unless there is an alternative way to mix it? I used to use your green label with no issues?
Date published: 2018-09-11
Rated 3 out of 5 by from Bubbles and foam in bottles I'm new to using this formula. Three out of three bottles have been full of bubbles and foam. Is this normal for this formula. I'm using on my new baby that has been having issues with spit up and gas.
Date published: 2018-09-08
Rated 5 out of 5 by from Recommend it. Been using for my new born. It’s gentle for her and i am so happy for it.
Date published: 2018-09-07
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Has your family been affected by Hurricane Florence?

If you or someone you know has been affected, find out how Similac® can help.