Similac® Advance®


For your baby's first year

Similac Advance Stage 1 is designed to be closer than ever to breast milk*, and has OptiGRO™ to support your baby's brain
and eye development.

* Reformulated to better match the average caloric density of breast milk; available in most Similac formulas
Similac® Advance®
tummy care guarantee
Parents know that every tiny tummy is unique.

So if your baby's tummy doesn't agree with a Similac product,
you can try another one FREE*

*Refund of purchase price (excluding taxes and shipping) on select products
only. Limit 2 refunds per household. Must redeem within 30 days of purchasing
alternative formula.

Similac has OptiGRO

OptiGRO is our unique blend of DHA, Lutein, and Vitamin E;
these important ingredients are found in breast milk.

  • DHA   for brain and eye development

  • Lutein   to support eye health

  • Vitamin E   an important nutrient found in breast milk to support developing cells

OptiGRO is available in most Similac formulas.

OptiGRO is getting a new look, too!


Formula types

  • Powder formula
  •  |  Ready To Feed formula
Powder formula
Ready To Feed formula

Powder formula

Just add powder formula to water and mix.
Similac® Advance® SimplePac

Available in the Similac® SimplePac®

Mom Preferred. Similac SimplePac. And chosen easier to use 3 to 1 over the Enfamil® refill tub.*

*Formula Package Study 2010.

Feeding solutions

It takes time for a baby’s digestive system to mature, so don’t assume
you have to switch from Similac Advance if your baby is being fussy. 

Always talk to your pediatrician about feeding issues before making a switch.

Before switching, try these suggestions:

  • Use a different bottle or nipple.
  • Use a different burping position.
  • Adjust your body position.
  • Use liquid formula instead of powder.

Have more feeding questions?

Go to Feeding Expert 
Keep learning about your baby's development every week
Get nutrition guidance and feeding help delivered right to your inbox.  
Join Similac® StrongMoms® now.   

Your Similac StrongMoms membership is free, and includes:
  • Expert nutrition guidance for your pregnancy
  • Weekly updates on how your baby is developing and growing
  • Up to $329 in membership benefits
Offers may vary.  
Get up to $329† in great offers. Sign up now >

Rated 4.9 out of 5 by 394 reviewers.
Rated 5 out of 5 by Not very expensive My baby is happy, I'm very happy. September 29, 2015
Rated 5 out of 5 by I've tried several formulas and this one has worked best. I tried a few different formulas after I was no longer able to breastfeed my baby. This one has worked very well for us! It did not cause any extra gas or spit up. September 26, 2015
Rated 5 out of 5 by Great product! When transitioning from breast milk to formula. We tried a few different formulas and my daughter LOVED this one. It even smells and tastes pleasant compared to other competitors! Would recommend to anyone. September 26, 2015
Rated 5 out of 5 by affordable affordable, great taste compared to enamil. Baby never had a problem with constipation September 24, 2015
Rated 4 out of 5 by love the easy of use we are always on the go so using the powered formula saves us from always having to have a cooler with us and it makes it quick to mix up and feed our daughter just wish the cost was a bit lower September 19, 2015
Rated 5 out of 5 by Similac products have been great for our daughter! We have used Similac for our daughter through many different phases. All have been extremely helpful! We would recommend using Similac formula to any new parents. September 15, 2015
Rated 5 out of 5 by Lovely and healthy product My baby loved it. He looks healthier. And I knew he was taking the right milk. I definitely loved using Smilac Advance complete nutrition for my baby. September 15, 2015
Rated 5 out of 5 by Great for babies who can't drink just any formula! My son is just a little sensitive to formulas especially Enfamil. He rarely spits up and has an easy time digesting the Similac Advance formula. September 13, 2015
  • 2015-10-03T11:52:21.618-05:00
  • bvseo_lps, prod_bvrr, vn_prr_5.6
  • cp-1, bvpage1
  • co_hasreviews, tv_394, tr_394
  • loc_en_US, sid_sim-prod-300, prod, sort_default
2 3 4 5 ... 14 next>>
  • bvseo_sdk, net_sdk,
  • CLOUD, getContent, 31ms