Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months


Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch up.

Help support her development in the first full year by feeding her Similac NeoSure, a nutrient-enriched* formula for babies who were born prematurely.


Supports excellent growth during baby’s first year.1

  • Increased protein, energy, vitamins, and minerals compared to term infant formula
  • Extra calories for growth
  • Calcium and phosphorus for baby’s growing bones

Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula.1 Has OptiGRO to support your baby's brain and eye development.

Learn more about the nutritional needs of your preemie.

Get tips for keeping your baby’s immune system strong.

Learn why catch-up growth is important.

* Increased protein, vitamins, and minerals compared to term infant formula.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107:638-689.

Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

Similac NeoSure 13.1 oz formula with Iron for preemies 13.1-oz Powder

Similac NeoSure 13.1 oz formula with Iron for preemies 1-qt Ready to Feed

Similac NeoSure 13.1 oz formula with Iron for preemies 2-fl-oz Ready to Feed

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
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Rated 4 out of 5 by from Good product, but expensive My baby was born at 35 weeks and was put on neosure in the NICU. It's helped him double his weight in just 6 weeks. But the product is very expensive and I don't qualify for state aid. Also it's been giving him terrible gas pains and constipation.
Date published: 2017-06-13
Rated 5 out of 5 by from works great with premies for weight gain this help my premie gain weight and keep her maintain weight while breastfeeding. easy to digest on her little tummy.
Date published: 2017-06-10
Rated 5 out of 5 by from Our Preemie loves it as much as we do! I started using Neosure to fortify my breastmilk when my son came home from the NICU. He was born at 29 weeks and had a 55 day stay at the NICU. Our doctor recommended a 1/2 tsp of Neosure for every 4 ounces of breastmilk and our preemie has handled it extremely well. My husband and I were worried about introducing formula to our son so early, but our worries were gone once we saw how well he tolerated it, and how he gained over the past few months. His birth weight was 2lbs 11oz. Five months later he is now 11lbs 3oz. Our only concern is that we will be needing to switch to all formula and although we want to continue to use Neosure, from a financial standpoint we are concerned about the price. Does your company offer any promotions or rewards for Neosure to help parents with the cost of Neosure? My husband and I really want to use Neosure until he is off formula completely.
Date published: 2017-06-05
Rated 4 out of 5 by from Excellent Gains... My daughter was born 4/11/17, 4lbs (3lbs 11oz discharge) at 35wks due to being eclampsia and thanks to God, she only had one issue and that was the bilirubin levels high because of me having HELLP along with my high BP. Now, I will say that her weight gain was incredible. I went through 2 cases of the 2oz already made in a month that was added with my breast milk. At first, she wouldn't drink the pure NeoSure, but combined with my milk, she would take it. The 1st month, she gained 2lbs and I'm not sure if the NeoSure or if it's my diet that's contributing to her excessive gassiness creating this horrible disconfort. I never thought the supplement could cause the gas bubbles, so I'll be omitting the other milk to make sure if she continues cause she's became more fussy than normal. Now, if I don't feel like breastfeeding or I can't, I'll give her just pure NeoSure (which she'll drink), however, she spits up way more with it especially if you don't burp her afterwards. For the women who say they have a hard time finding the product, if you have Amazon or AmazonPrime, my mom bought me cases containing 48 tiny bottles. You can find virtually anything there and get them quickly if you have Prime.
Date published: 2017-06-01
Rated 1 out of 5 by from 2-fl-oz Ready to feed is UNAVAILABLE at any store My son is at 31 weeks and this is the recommended baby formula from the hospital. We got discharged from the hospital FINALLY last 5-5-17. I travel a lot and having a ready to feed bottle is a good thing to have. I went to walgreens, CVS, 3 different branches of walmart, and did online research. I CANNOT FIND ONE!! until last friday, I went to walmart online website and I saw that it was available now. So I ordered 24pcs of it through walmart last Friday 5/12/17 coz it states in their website that they have it. The package came in this morning and they send me the wrong kind. They send me a can for 6-12 months old 3cans for DIARRHEA. I called it in and they apologized for sending me the wrong one and that they will refund my pay because they don't have that milk available. My son is a month old and being a premie baby is stressful as it is. Let alone the milk that u needed is NO WHERE TO BE FOUND. Please help me getting this milk SIMILAC.
Date published: 2017-05-17
Rated 1 out of 5 by from My baby takes this My baby girl is in so much pain from this formula. I hate the gas and constipation and I hate giving it to her. It breaks my heart that she is in pain. She was born at 35 weeks cause I was really sick and we both about died.. Because I had pre eclammpsia and help syndrome. We have to give it to her twice a day. And I refuse to.
Date published: 2017-05-15
Rated 3 out of 5 by from Great for weight gain... that's about it. Daughter was born at 33 weeks 4 days, and had a 6 week NICU stay. She was put on this formula in the NICU. This formula is amazing for weight gain, she puts on an average of a half a pound a week, BUT the gassyness, constipation and pain that it causes on a daily basis are unreal. Similac! PLEASE CHANGE YOUR FORMULA! If 99% of the reviews for a product complain about gassyness, constipation and/or pain, don't you think it would be a clue to do something about it?! ONLY RECOMENDING THIS PRODUCT FOR THE WEIGHT GAIN AND NITRITIONAL VALUES. THE SIDE EFFECTS ARE ALMOST NOT WORTH IT!
Date published: 2017-05-15
Rated 5 out of 5 by from The best This is the best formula ever!my baby girl was born 26 weeks, being a micro preemie this formula did the best,she never had any problems with it,no gassy, no colic,none!they used this formula while in NICU ,now at home I'm still using it,until she's 1 year adjusted, it's full of minerals, vitamins, nutrients It's our life saver!!!! Thank you so much SIMILAC!!!!
Date published: 2017-05-06
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