Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months


Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch up.

Help support her development in the first full year by feeding her Similac NeoSure, a nutrient-enriched* formula for babies who were born prematurely.


Supports excellent growth during baby’s first year.1

  • Increased protein, energy, vitamins, and minerals compared to term infant formula
  • Extra calories for growth
  • Calcium and phosphorus for baby’s growing bones

Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula.1 Has OptiGRO to support your baby's brain and eye development.

Learn more about the nutritional needs of your preemie.

Get tips for keeping your baby’s immune system strong.

Learn why catch-up growth is important.

* Increased protein, vitamins, and minerals compared to term infant formula.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107:638-689.

Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

Similac NeoSure 13.1 oz formula with Iron for preemies 13.1-oz Powder

Similac NeoSure 13.1 oz formula with Iron for preemies 1-qt Ready to Feed

Similac NeoSure 13.1 oz formula with Iron for preemies 2-fl-oz Ready to Feed

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
Similac logo

New Moms

Join Similac® StrongMoms® Rewards for up to $400* in customized benefits, free gifts and exclusive savings.
Strongmom Decor Dsk
SIGN UP *Offers may vary.
Rated 4 out of 5 by from Very pleased Used this to fortify some breastmilk bottles with my 33weeker. After stopping pumping and giving away a TON of frozen breastmilk, I ran out at 8 months (still nursing before and after daycare) so she is on similac neosure for about two big bottles per day. Have had no issues with gas or constipation as others mentioned. Only thing is the price, obviously, and I do wish they sold in LARGER QUANTITIES. We go through about a can per week right now and I try to buy when there's a sale or coupon.
Date published: 2017-08-17
Rated 3 out of 5 by from Issues with the powder I'm a first time mom and I had my baby at 33 weeks and 5 days and was in the nicu for 18 days. They gave her the neosure for premies ready to use twice a day to give her extra calories the closer it got to her going home. They sent her home with about two weeks of the 2oz bottles of the ready to use and a can of the powder. No real issues with the 2oz mix besides her spitting a little of it up after feeding it to her. Once we started the powder, she spit up a lot more, had a lot of mucus and was very gassy and constipated and its getting worse. She is a little over 6 weeks and the gas and constipation is so bad now that she will lift/stand on her leggs sticking her butt out while crying/screaming to the top of her lungs and they want her on it twice a day since I bf her.
Date published: 2017-08-15
Rated 4 out of 5 by from Pricey but worth it My son was born at 32 weeks and has been healthy all along (now 4 months). He's on Neosure exclusively now after supplementing with breast milk. He was 4lbs 9oz at birth and has thrived. He's now in the 60th percentile for growth for his actual age. I only wish this formula was offered in a more economical size. We use 2-3 cans a week and it's pretty expensive for us. But we'll stick with it until the pediatrician tells us otherwise.
Date published: 2017-08-10
Rated 4 out of 5 by from Great for weight gain but... My son was born at 35 weeks but was only 3lbs 14oz. The hospital nicu put him on the premade (ready to feed) bottles and he did great. Hardly lost any weight after birth and was at 4lbs 8oz in less than 2 weeks. Since we came home we had to switch to the powder (WIC only pays for powdered cans) and he's always in so much pain from gas and spits up after every feeding. He never fussed or cried at all til we switched to the powder. I definitely love the fact that he's gaining weight so well just wish it didn't make him feel so bad.
Date published: 2017-08-07
Rated 5 out of 5 by from Excellent for extra calories Love this product just wish it came in bigger cans. My son was born at 36 weeks and a day and it was recommended to gain weight. I make it with 21 ounces of water and 14 scoops of powder for the bottles throughout the day. He gets 27 calories from this rather than 22. It's how they were feeding him in the NICU.
Date published: 2017-08-07
Rated 4 out of 5 by from Great for growth but causes tumny aches Our son was born at 39 weeks, 6 days but was SGA (small for gestational age). I tried breastfeeding but he won't latch and I couldn't get my milk to produce or come out after pumping and trying to hand express. The nurses at the hospital suggested this formula to help him gain weight. He gained ounces in days and is steady growing. Lately we've noticed he's having more gas and spit up after feedings, crying and arching his back. We did switch to the powder formula once we left the hospital, so we may need to go back to the liquid version.
Date published: 2017-08-07
Rated 4 out of 5 by from Stick with liquid! Our baby was born 36wks NiCU they gave him neosure 2oz ready to feed bottles. We switched to powder formula neosure when we got home and he became gassy, constipated and fussy. We have gone back to the 2oz ready to feed bottles and the liquid 1qt and he is not constipated and less gassy. Hopibg once we come off the neosure we can try powder again, liquid is expensive!
Date published: 2017-08-02
Rated 4 out of 5 by from It's alright I had to have my baby boy at 36 weeks due to preeclampsia. He's been gaining weight and doing real well, but as of a couple days ago I've notice he's been having issues going poo and he's been really gassy. It breaks my heart seeing him like this :(
Date published: 2017-08-01
  • y_2017, m_8, d_22, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_1.0.0-hotfix-1
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_267
  • loc_en_US, sid_sim-prod-510, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING), SortEntry(order=FEATURED, direction=DESCENDING)]
  • clientName_similac
  • bvseo_sdk, net_sdk,
  • CLOUD, getReviews, 27ms