Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months


Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch up.

Help support her development in the first full year by feeding her Similac NeoSure, a nutrient-enriched* formula for babies who were born prematurely.


Supports excellent growth during baby’s first year.1

  • Increased protein, energy, vitamins, and minerals compared to term infant formula
  • Extra calories for growth
  • Calcium and phosphorus for baby’s growing bones

Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula.1 Has OptiGRO to support your baby's brain and eye development.

Learn more about the nutritional needs of your preemie.

Get tips for keeping your baby’s immune system strong.

Learn why catch-up growth is important.

* Increased protein, vitamins, and minerals compared to term infant formula.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107:638-689.

Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

Similac NeoSure 13.1 oz formula with Iron for preemies 13.1-oz Powder

Similac NeoSure 13.1 oz formula with Iron for preemies 1-qt Ready to Feed

Similac NeoSure 13.1 oz formula with Iron for preemies 2-fl-oz Ready to Feed

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
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Rated 4 out of 5 by from Had to learn but love it My son was born at 34 weeks.. 4 lbs 2 oz.. while in NICU this was the formula used. When we brought him home at 37 weeks, I noticed it made him extremely gassy and fussy so I switched to a different brand briefly until learning I could get neosure for free (without wic) so the Doctor recommended us keep him on the neosure. I wasn’t sure because I hate seeing my baby in pain being a first time mother, however, my sister who’s a mother of 5 grandmother of 2 recommended this gas medicine, mylicon and it has been nothing but great for my little guy! He’s now 11 pounds at 11 weeks. Sleeps well with the combo of the neosure and gas meds occasionally! We’re happy!
Date published: 2017-10-11
Rated 1 out of 5 by from Horrible constipation This product is absolutely horrible for lactose sensitive babies. My lo is so constipated/gassy all he does is cry. There needs to be a lactose free version with the higher calorie count. My peds doctor refuses to take him off this formula.
Date published: 2017-10-10
Rated 3 out of 5 by from This product isn't that great When I got to bring my little one home I could produce enough breast milk so they had him on this formula. Come to find out, it's made him constipated and we have had to water it down. His pediatrician wanted to change it and WIC won't do it so it's still expensive.
Date published: 2017-10-04
Rated 3 out of 5 by from This product is somewhat great My daughter was born at 28 weeks and while I'm the body, they gave her the premade small 2 oz bottles. When i took her home, u started giving her the powder. To my disgust, it made her very ill, gasy and bloated. After drinking it, she spits up a lot. I would recommend the premade but not so much the powder. Especially the fact that the powder is expensive and doesn't last my daughter long
Date published: 2017-10-04
Rated 4 out of 5 by from I love the milk for my son. My son was born at 35 weeks weighing 5 lbs 1oz. He is now 7 weeks old and just a chunky little thing. I love the milk, only downside is the cost. The milk is so expensive for me. I wish there were better coupons.
Date published: 2017-10-01
Rated 5 out of 5 by from Excelente for my twins girl's I have twins girls that was born at 36 weeks , with this formula my girls with only 3 weeks old the are over 7 pounds each.. they are really active and I love it..
Date published: 2017-09-30
Rated 5 out of 5 by from Neosure is amazing ! My daughter was born 5 weeks early when she was born she weighed 6 pounds but then dropped down to 5 pounds 5 ounces , they were feeding her the neosure in the special care and when we came home her pediatrician recommended she still use it so we have gotten it from wic with a prescription, she is now one month old and is perfectly healthy weighing 7 pounds and 5 ounces mind you the first week she was home and using the neosure powder she gained a whole pound and 3 ounces !!!
Date published: 2017-09-30
Rated 5 out of 5 by from Awesome My girls are 4 months old and this formula has been awesome since day one. I love it! Wondering if their are coupons for Neosure since the cans are a little more pricey?
Date published: 2017-09-29
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