NEW VALUE-SIZE CAN—Get Over 70% More*

Similac® NeoSure® VALUE SIZE Now Available Exclusively At Walmart

Similac® NeoSure® Formula Value size can be found at Walmart

Makes 74% more vs the 13.1-oz powder can. That’s 16 more 4-fl-oz bottles.*


Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months


Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch up. During her first full year, feed her Similac NeoSure, a nutrient-enriched formula for babies who were born prematurely, and help support her development.

Similac NeoSure is now available in a NEW value-size can, which provides over 70% more formula*-available at Walmart.


Supports excellent growth during baby’s first year.1

  • Increased protein, energy, vitamins, and minerals compared to term infant formula
  • Extra calories for growth
  • Calcium and phosphorus for baby’s growing bones

Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula.1 Has OptiGRO® to support your baby's brain and eye development.

Learn more about the nutrition needs of your preemie.

Get tips for keeping your baby’s immune system strong.

Learn why catch-up growth is important.

* Versus NeoSure 13.1-oz powder.
† Increased protein, vitamins, and minerals compared to term infant formula.
‡ Compared to term infant formula.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107(4):683-689.

Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

22.8-oz Powder

13.1-oz Powder

1-qt Ready to Feed

2-fl-oz Ready to Feed

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
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Similac NeoSure Reviews

Rated 5 out of 5 by from Twins Mom My twin girls were born at 34 weeks and we’re given Neosure in the NICU. I’ve had a great experience with this formula it is a bit expensive at an average $20 a can. I have found it as low as $17 which is great. Our twin girls are 7 months (6months adjusted) and eating almost 1 can a day at this point. Honestly wouldn’t have gone with any other formula..we’ve noticed the weight gain and are happy with how much they’ve grown.
Date published: 2019-05-15
Rated 4 out of 5 by from Great but wish it came in bigger size Our preemie was put on this in the NICU and we have remained on it since. She is now 4 months and gaining weight perfectly. Her pediatrician is very happy with her weight gain and wants us to keep her on this until she is around 6 months. I just wish it came in a bigger container! At first, she wasn't eating as much so the smaller container worked perfect but now we are going through a container every couple days and I live at the grocery store! Why can't it come in a bigger size like the other products?
Date published: 2019-05-13
Rated 4 out of 5 by from Great Nutritional Content but Causing Gas My daughter was born at 34 weeks and started on Neosure in the NICU. I use it to supplement my breastmilk. She is gaining weight just fine, but is extremely gassy. Within a few minutes of drinking it, she is extremely uncomfortable and it is hard to get her back to sleep, which is tough in the middle of the night. I am definitely considering switching to a different brand even though her pediatrician loves this brand. I can’t take the suffering too much longer. It is also difficult to find the ready to feed bottles, we order them online and it’s quite pricey, which would not bother me if it was well tolerated by my daughter. We were planning to switch to the powder but after reading other reviews here, it would not help with the gas problem.
Date published: 2019-05-08
Rated 5 out of 5 by from My little one loves it !!!! My little one is 34 weeks preemie born at 3 pound 11 ounce. He loves neosure and gaining weight as expected. He is 2 month 3 weeks now at 8.2 pounds. Neosure is recommended by my pediatrician as well.
Date published: 2019-04-29
Rated 4 out of 5 by from Great but with some gas and constipation My baby came at 25 weeks. I first used it to fortify his breast milk but now he’s just on the formula. He is gaining weight just fine, however, he often has the worst gas. I usually give him gas relief drops every feed. He’s also recently had constipation. The doctor suggested a probiotic. So clearly even though it causes some tummy issues, it’s worth it because his pediatrician did not switch his milk (which is usually what they do with tummy issues). I’m pleased with his growth and development so far just wish it don’t come with so many tummy problems.
Date published: 2019-04-15
Rated 5 out of 5 by from My son its gaining weight and growing fast he is 2 months now and he is a big boy My son its gaining weight and growing fast grate formula
Date published: 2019-04-11
Rated 5 out of 5 by from This product helps promote proper growth My daughter was born early so to a rupture. She loves the taste of this formula and is growing at a proper rate now. The hospital I was at gave her the Enfamil Neroupro but she kept spitting it up and screaming because she was hungry. I never wanted her on enfamil so I asked about other options and eventually I did my own research and found this product. It’s already hard having a preemie but a preemie that wants to eat but is losing weight is hard when all you want is to provide them with what they need. I love this product. It’s definitely helping my daughter grow at the proper weight without over weight, and the perfect amount of calories for her growing little body.
Date published: 2019-04-09
Rated 5 out of 5 by from Great formula for preemie Our little angel was born at 28 weeks. She was 2lbs 11oz and stayed in the NICU for a little over 2 months. She is now 4 months old and almost 8 pounds. This formula worked miracles on catching her up with the size she should be. I can never thank Similac enough for helping my sweet girl catch up in life. This is the only formula we give her. I swear by Neosure.
Date published: 2019-04-01
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