Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months


Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch up.

Help support her development in the first full year by feeding her Similac NeoSure, a nutrient-enriched* formula for babies who were born prematurely.


Supports excellent growth during baby’s first year.1

  • Increased protein, energy, vitamins, and minerals compared to term infant formula
  • Extra calories for growth
  • Calcium and phosphorus for baby’s growing bones

Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula.1 Has OptiGRO to support your baby's brain and eye development.

Learn more about the nutritional needs of your preemie.

Get tips for keeping your baby’s immune system strong.

Learn why catch-up growth is important.

* Increased protein, vitamins, and minerals compared to term infant formula.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107:638-689.

Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

13.1-oz Powder

1-qt Ready to Feed

2-fl-oz Ready to Feed

For babies who were born prematurely

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
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Similac NeoSure Reviews

Rated 5 out of 5 by from Great product Our little miracle baby, Ruby, was born at 37 weeks via c section!! She was only 3 pounds 11 ounces and had to stay in the special care nursery for an extra two weeks. She was put on neosure from day one and started growing like crazy. She gained 10 ounces in a week and in a month gained 3 pounds 6 ounces. She's doing great and is still on it today at three and half months. She tolerates it well and never spits up!! She will be staying on it until at least 6 months per her doctor but we will switch her over to another Similac product then because it's been so good for her. It is expensive but the checks for money off you send me really help out!!
Date published: 2019-03-13
Rated 5 out of 5 by from Great My daughter was born at 28 weeks and weighed 2 pounds 4 ounces. Neosure was used to fortify my breastmilk and now that I'm unable to produce milk it was an easy transition to solely using Neosure. She now weighs 4 pounds 10 ounces.
Date published: 2019-03-05
Rated 5 out of 5 by from Amazing My triplets were born at 24 weeks. They have been on Neosure since we came home from the NICU, I wouldnt recomend anything else to a family with a preemie. It's really helped them gain weight.
Date published: 2019-03-05
Rated 5 out of 5 by from Great Product My son was born December 2018 at 27 Weeks and 4 Days. Throughout his journey, NEOSURE has been the only product to not only give his body what it needs to have steady growth but its light on his stomach compared to other products! This stuff does wonders! He started off at 1LB 13oz and is now at 6LBS 10oz!
Date published: 2019-03-02
Rated 5 out of 5 by from Awesome product My son was born prematurely at 31 weeks and weighed 2lbs 6oz. We had to stay in the NICU for 2months, 2days. My breastmilk was fortified with Neosure to help with his weight gain. He now weighs 5lb, 15oz and still growing. Though he gets gasy, it's provides him with all the nurients he needs to help him grow. I will definitely recommend Neosure as the go to formula for your premature baby.
Date published: 2019-03-01
Rated 4 out of 5 by from Great nutrients, but hard on tummies. My baby was born prematurely at 34 weeks and weighed 4lbs 2oz. We spent a month in NICU where they supplemented with Neosure22, however now at 2 months old-thats all he eats. Its a great product for weight gain and nutrients as he now weighs 8lbs 2oz, however it has caused so much pain, discomfort, and gas that it absolutely breaks my heart. I wish it was gentler on tummies. I have considered changing to a different formula just because of the pain he is constantly having.
Date published: 2019-03-01
Rated 3 out of 5 by from Great product. My granddaughter was born at 37weeks, at 5lb 6oz, and dropped weight as soon as we left the hospital. We needed to put the weight on her, so we tried NeoSure. It has worked, but we seem to be having issues with her being gasey, constipated, and spitting up. We switched formulas, thinking it was the formula, but came back to the NeoSure it seems to be the only one that works for. But we are still having the problem of her being gasey and constipated. Any suggestions?
Date published: 2019-02-28
Rated 4 out of 5 by from Finally Gaining Weight! My little girl was born 1-14-19, she was considered late preterm at 36 weeks and weighed 5lbs 9ozs at birth, she just hit 6 weeks old and is now 8lbs! She has problems with gas and spitting up but is still putting on weight which is what we've been praying for. I would recommend this product to other NICU parents (we had a 2.5 week stay) and glad the hospital had recommended it to us. My little munchkin is continuing to make progress and big strides! Thank you!
Date published: 2019-02-26
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