Has your family been affected by Hurricane Michael?
Find out how Similac® can help >


Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months


Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch up.

Help support her development in the first full year by feeding her Similac NeoSure, a nutrient-enriched* formula for babies who were born prematurely.


Supports excellent growth during baby’s first year.1

  • Increased protein, energy, vitamins, and minerals compared to term infant formula
  • Extra calories for growth
  • Calcium and phosphorus for baby’s growing bones

Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula.1 Has OptiGRO to support your baby's brain and eye development.

Learn more about the nutritional needs of your preemie.

Get tips for keeping your baby’s immune system strong.

Learn why catch-up growth is important.

* Increased protein, vitamins, and minerals compared to term infant formula.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107:638-689.

Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

13.1-oz Powder

1-qt Ready to Feed

2-fl-oz Ready to Feed

For babies who were born prematurely

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
Similac logo

New Moms

Join Similac® StrongMoms® Rewards for up to $400* in customized benefits, free gifts, and exclusive savings.
Strongmom Decor Dsk
SIGN UP * Offers may vary.

Similac NeoSure Reviews

Rated 2 out of 5 by from Expensive My grandson was born at 29 weeks, momma had preeclampsia. She tried nursing, didn't work, baby was put on Neosure. This stuff is very expensive and does seem to cause gas. It's hard for the parents to buy this because it is so expensive. I feel like we are all being taken advantage of because of the special needs for our preemies. And yes, I know it has all of the vitamins and nutrients but does it have to cost an arm and a leg? I say shame on you Similac.
Date published: 2018-10-15
Rated 3 out of 5 by from This product is helpful but at the expense of a gassy uncomfortabe baby My baby was born at 34 weeks weighing 3lbs 11oz. He stayed in NICU 12 days and was immediately put on Neosure 22 for weight gain while also supplementing with breast milk. During the first month our baby was taking Neosure just fine but by month 2 is when we noticed fewer poops, more spit up and extreme gassiness. Although we were advised to give two servings of Neosure daily while also taking breast milk our baby seem to develop an intolerance for Neosure. Our Pediatrician suggested we give baby half and half meaning 1/2 Neosure and 1/2 Pro- Advance. We had least spit ups and he still gained but did not poop often. We just purchased Total Comfort and I am looking forward to seeing some relief for our baby based on all the reviews about Total Comfort.
Date published: 2018-10-02
Rated 2 out of 5 by from Few problems Everything was fine until my baby made 2 months I noticed she get extremely constipated after drinking neosure. She cries & fusses .. I asked the doctor what can I do they told me try apple juice, it helps a little but not much . I hate that she have to go through this everyday
Date published: 2018-09-27
Rated 5 out of 5 by from My preemie loves it. My little one was born at 29 weeks, and spent 2 months in the NICU.. due to my lack of production of breast milk, they started weaning her at 7 weeks to neosure from breast milk.. now she is almost 9 months, and going thru about 3 cans a week. I agree the cost definitely adds up, and she stays gassy, but neo sure has definitely kept her weight gain on track. Another thing I battle is actually finding neosure. Everytime I go to buy it, I have to hit 3-5 stores before lucking out. There must be a lot of preemies on neosure out there!
Date published: 2018-09-27
Rated 5 out of 5 by from My preeme baby My baby was born at 35 weeks, spent 2 weeks in the hospital but they weren't giving him this kind but when I saw his pediatrician she recommended this kind of formula and also sent a referral to wic so they would pay for it! Definitely ask if you can be put on wic if using this product, it is very expensive.
Date published: 2018-09-24
Rated 4 out of 5 by from NeoSure: Formula for Weight Gain and Gas Production Our premie was born at 29 weeks and 2 days and stayed in the NICU for about 10 weeks. He was sent home on alternate breast milk and Neosure 24 combination. He was fed in quite measured quantities in the NICU, which, BTW, we always thought was less than sufficient for him (but we understand their cautious approach). At home we offered more and he took it happily. We believe that his excellent weight gain in the early weeks at home is due to this product, however, after about 10 weeks at home, his weight gain has reduced pace a little. He likes breastmilk over Neosure for sure, but he doesn't mind Neosure when hungry :) We notice that he can tolerate less volume of Neosure when compared to breastmilk, We also see more frequent spit-ups, and throw-ups with Neosure, both of these may be gas related. We also noticed that he goes less often when on Neosure (we have tried experimenting changing levels of Neosure). We tried some pear juice but that did not help much and was cutting into his calories. We wish there a less gassy version of this product.
Date published: 2018-09-23
Rated 2 out of 5 by from So expensive and causes constipation/gas pains My preemie was born at 35 weeks and this is the formula my ped recommended we used at home. I’m not sure how anyone can afford to buy this weekly and then have preemie medical bills ontop of it. Something needs to be made that’s affordable and does the same job for our little ones. Crazy :( Also my baby squirms in pain every time he eats. Along with arching his back and grunting this formula gives him constipation and ALOT of gas. I feel so bad.
Date published: 2018-09-19
Rated 3 out of 5 by from Product has been great for my baby but SOOO EXPENSIVE My baby was born at 35 weeks, but stopped growing at about week 31. He was 3lbs 10oz. The NICU sent us home with neosure, and the pediatrician recommended that he stay on it. He is about to rub out again. It's going to break the bank. There should be something out there for premie babies that doesn't break the bank.
Date published: 2018-09-14
  • y_2018, m_10, d_17, h_17
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.8
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_347
  • loc_en_US, sid_sim-prod-510, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING), SortEntry(order=FEATURED, direction=DESCENDING)]
  • clientName_similac
  • bvseo_sdk, net_sdk,
  • CLOUD, getReviews, 109ms
Has your family been affected by Hurricane Michael?

If you or someone you know has been affected, find out how Similac® can help.