Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months


Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch up.

Help support her development in the first full year by feeding her Similac NeoSure, a nutrient-enriched* formula for babies who were born prematurely.


Supports excellent growth during baby’s first year.1

  • Increased protein, energy, vitamins, and minerals compared to term infant formula
  • Extra calories for growth
  • Calcium and phosphorus for baby’s growing bones

Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula.1 Has OptiGRO to support your baby's brain and eye development.

Learn more about the nutritional needs of your preemie.

Get tips for keeping your baby’s immune system strong.

Learn why catch-up growth is important.

* Increased protein, vitamins, and minerals compared to term infant formula.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107:638-689.

Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

13.1-oz Powder

1-qt Ready to Feed

2-fl-oz Ready to Feed

For babies who were born prematurely

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
Similac logo

New Moms

Join Similac® StrongMoms® Rewards for up to $400* in customized benefits, free gifts, and exclusive savings.
Strongmom Decor Dsk
SIGN UP * Offers may vary.

Similac NeoSure Reviews

Rated 5 out of 5 by from This product has been amazing for my son. This milk has worked wonders for my 31 weeker he has gained on average 3lbs a month on it he just turned 6 months old and he has gained 13 lbs and grew 9 inches while on it. Thank you so much for making this milk for all the tiny babies out there.
Date published: 2019-02-06
Rated 5 out of 5 by from Great product (Awesome results) Neosure has worked well for my 29 weeker. She's gained weight and developed well with the formula. Initially there was constipation and gasiness. I stopped using nursery water, started boiling faucet water, mixing enough formula for 24 hours and refrigerating, and warming bottles slightly right before feeds. She immediately improved. We've cut costs by ordering in bulk from Amazon (significant savings).
Date published: 2019-02-03
Rated 2 out of 5 by from Not great for sensitive stomachs While the formula has great benefits in being higher calorie for premature babies, I have now had two babies on it that both experienced awful constipation and even worse reflux on this particular formula. Upon switching to Similac sensitive it was a night and day transition...reflux, gas and constipation instantly gone. My son was 34 weeks and had to be put on reflux medication while on this product which stopped upon changing formulas, our daughter was born 31 weeks and has not slept in a week she has been in so much pain, so I wouldn't recommend if your baby's tummy cant handle it.
Date published: 2019-01-30
Rated 4 out of 5 by from Great products Neosure has been great for my son. He was born 8 weeks early and right from the start the NICU was adding it to my breast milk bottles to help “fatten” him up. 6 months old and I have recently stopped breast feeding. He is doing just fine with his neosure bottles. Still gaining weight and growing beautifully.
Date published: 2019-01-29
Rated 5 out of 5 by from Helps my twins grow My twin girls were born early due to preeclampsia and I had to supplement my breast milk with neosure. It’s an expensive brand but it works! FYI u can get your babies doctor to write a prescription for this and your insurance will pay for the formula
Date published: 2019-01-25
Rated 3 out of 5 by from Not so great for sensitive stomach! Gave birth to a baby boy at 34.5. While in the ICN he was given Neosure and was having great results and no negative reactions. Fast forward to now, two weeks later and he's now getting upset stomach; constipation, colicky and cant pass gas well. We have an appointment scheduled with his pediatrician, I'm really hoping they can change his formula to something else.
Date published: 2019-01-25
Rated 4 out of 5 by from Great for weight gain but not for constipation My baby girl was born at 36wks1day. She had done awesome with Neosure until about 2 weeks ago. She is 7 weeks today. She stays constipated and fussy. She goes for her 2 month check-up in a few weeks and I’m going to see about changing her to another high calorie formula. It is very expensive also! There aren’t any coupons or help anywhere!
Date published: 2019-01-04
Rated 5 out of 5 by from Premie twins thriving because of Neosure! Our twins were born at 29 w 5 days at 3 lb 14 oz and 3 lb 2 oz. They primarily received Neosure in the hospital due to low milk production on my end. They were able to go home at 35 weeks 3 days and have been doing great ever since (now up to 15 and 13 pounds at 5 months - still on Neosure). We use Amazon subscribe and save to offset some of the additional cost, as it is definitely pricey, but it’s specialty so the price tag is understandable. We do plan to stick with other Similac products once the twins switch off Neosure as we’ve tested some of the other varieties (samples we received) and they’ve responded well.
Date published: 2019-01-01
  • y_2019, m_2, d_22, h_15
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.11
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_369
  • loc_en_US, sid_sim-prod-510, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING), SortEntry(order=FEATURED, direction=DESCENDING)]
  • clientName_similac
  • bvseo_sdk, net_sdk,
  • CLOUD, getReviews, 62ms