Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months


Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch up.

Help support her development in the first full year by feeding her Similac NeoSure, a nutrient-enriched* formula for babies who were born prematurely.


Supports excellent growth during baby’s first year.1

  • Increased protein, energy, vitamins, and minerals compared to term infant formula
  • Extra calories for growth
  • Calcium and phosphorus for baby’s growing bones

Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula.1 Has OptiGRO to support your baby's brain and eye development.

Learn more about the nutritional needs of your preemie.

Get tips for keeping your baby’s immune system strong.

Learn why catch-up growth is important.

* Increased protein, vitamins, and minerals compared to term infant formula.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107:638-689.

Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

13.1-oz Powder

1-qt Ready to Feed

2-fl-oz Ready to Feed

For babies who were born prematurely

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
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Similac NeoSure Reviews

Rated 4 out of 5 by from Great but with some gas and constipation My baby came at 25 weeks. I first used it to fortify his breast milk but now he’s just on the formula. He is gaining weight just fine, however, he often has the worst gas. I usually give him gas relief drops every feed. He’s also recently had constipation. The doctor suggested a probiotic. So clearly even though it causes some tummy issues, it’s worth it because his pediatrician did not switch his milk (which is usually what they do with tummy issues). I’m pleased with his growth and development so far just wish it don’t come with so many tummy problems.
Date published: 2019-04-15
Rated 5 out of 5 by from My son its gaining weight and growing fast he is 2 months now and he is a big boy My son its gaining weight and growing fast grate formula
Date published: 2019-04-11
Rated 5 out of 5 by from This product helps promote proper growth My daughter was born early so to a rupture. She loves the taste of this formula and is growing at a proper rate now. The hospital I was at gave her the Enfamil Neroupro but she kept spitting it up and screaming because she was hungry. I never wanted her on enfamil so I asked about other options and eventually I did my own research and found this product. It’s already hard having a preemie but a preemie that wants to eat but is losing weight is hard when all you want is to provide them with what they need. I love this product. It’s definitely helping my daughter grow at the proper weight without over weight, and the perfect amount of calories for her growing little body.
Date published: 2019-04-09
Rated 5 out of 5 by from Great formula for preemie Our little angel was born at 28 weeks. She was 2lbs 11oz and stayed in the NICU for a little over 2 months. She is now 4 months old and almost 8 pounds. This formula worked miracles on catching her up with the size she should be. I can never thank Similac enough for helping my sweet girl catch up in life. This is the only formula we give her. I swear by Neosure.
Date published: 2019-04-01
Rated 5 out of 5 by from Great product Our little miracle baby, Ruby, was born at 37 weeks via c section!! She was only 3 pounds 11 ounces and had to stay in the special care nursery for an extra two weeks. She was put on neosure from day one and started growing like crazy. She gained 10 ounces in a week and in a month gained 3 pounds 6 ounces. She's doing great and is still on it today at three and half months. She tolerates it well and never spits up!! She will be staying on it until at least 6 months per her doctor but we will switch her over to another Similac product then because it's been so good for her. It is expensive but the checks for money off you send me really help out!!
Date published: 2019-03-13
Rated 5 out of 5 by from Great My daughter was born at 28 weeks and weighed 2 pounds 4 ounces. Neosure was used to fortify my breastmilk and now that I'm unable to produce milk it was an easy transition to solely using Neosure. She now weighs 4 pounds 10 ounces.
Date published: 2019-03-05
Rated 5 out of 5 by from Amazing My triplets were born at 24 weeks. They have been on Neosure since we came home from the NICU, I wouldnt recomend anything else to a family with a preemie. It's really helped them gain weight.
Date published: 2019-03-05
Rated 5 out of 5 by from Great Product My son was born December 2018 at 27 Weeks and 4 Days. Throughout his journey, NEOSURE has been the only product to not only give his body what it needs to have steady growth but its light on his stomach compared to other products! This stuff does wonders! He started off at 1LB 13oz and is now at 6LBS 10oz!
Date published: 2019-03-02
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