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NEW VALUE-SIZE CAN—Get Over 70% More*

Similac® NeoSure® VALUE SIZE Now Available Exclusively At Walmart

Similac® NeoSure® Formula Value size can be found at Walmart

Makes 74% more vs the 13.1-oz powder can. That’s 16 more 4-fl-oz bottles.*


Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months


Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch up. During her first full year, feed her Similac NeoSure, a nutrient-enriched formula for babies who were born prematurely, and help support her development.

Similac NeoSure is now available in a NEW value-size can, which provides over 70% more formula*-available at Walmart.


Supports excellent growth during baby’s first year.1

  • Increased protein, energy, vitamins, and minerals compared to term infant formula
  • Extra calories for growth
  • Calcium and phosphorus for baby’s growing bones

Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula.1 Has OptiGRO® to support your baby's brain and eye development.

Learn more about the nutrition needs of your preemie.

Get tips for keeping your baby’s immune system strong.

Learn why catch-up growth is important.

* Versus NeoSure 13.1-oz powder.
† Increased protein, vitamins, and minerals compared to term infant formula.
‡ Compared to term infant formula.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107(4):683-689.

Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

22.8-oz Powder

13.1-oz Powder

1-qt Ready to Feed

2-fl-oz Ready to Feed

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
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Similac NeoSure Reviews

Rated 3 out of 5 by from My baby loves this formula but wallet hates it My baby was a nicu baby she was born small and has a small condition, which I’m hoping she will out grow, I absolutely love this formula and it smells great too and my baby loves it, but really expensive and I wish there was a bigger size I’m struggling to get her this formula but she needs it her pediatrician recommended it for her being that she is so small and she needs the extra calorie intake I wish this formula can be more affordable or at least coupons to help me with the cost
Date published: 2019-07-19
Rated 4 out of 5 by from Perfect for my twins, but expensive My twins were born at 32 weeks, and spent 5.5 weeks in the NICU. They were 3 and 4lbs at birth and have doubled their weights in two months thanks to Neosure! They have thrived on Neosure but insurance won’t help cover and I’m not sure I can afford the steep cost for 10 more months for them to continue on the formula.
Date published: 2019-07-16
Rated 2 out of 5 by from Great formula, but expensive My son was born premature and stayed in NICU for 2 months. NICU discharged him on Neosure 2oz bottles, the only formula that helped him gain some weight in the hospital. He will only take Neosure ready to feed and would not take the powder version. He easily goes through about $27 of Neosure each day (we switch between Neosure ready to feed 2oz and 32oz). We used to get the 6 bottles per box of Neosure 2oz for $9, but now they change it to 4 bottles per box for $7. My son will need to be on Neosure for all least 9 months more. Very disappointed at why they increase the price on these specialized formulas. We've been looking for more affordable alternatives...
Date published: 2019-07-13
Rated 4 out of 5 by from Good but Expensive This is a good product that delivers as promised. Unfortunately the price is steep, particularly when you have twins. I hope to be able to continue my twins on the formula though finances may require a change.
Date published: 2019-07-11
Rated 4 out of 5 by from Product is great, price is terrible! My boys have all been preemies, and the hospital has me fortifying my breast milk with neosure. This time, my newest little one (34 weeker) is in less than the 1st percentile for BMI, and has needed the weight gain desperately. However, neosure makes him gassy, and my milk is drying up. There's no reasonable way that I can afford the cost of 100% neosure feedings for him long term, even though he's been growing well on it. Since this formula is not covered by any assistance programs, I will probably have to switch formulas soon, to something more affordable, and hope for the best.
Date published: 2019-07-03
Rated 4 out of 5 by from Helped my tiny humans grow, but killing my wallet. My twins were born at 31 weeks, when I couldn't keep up with their needs with breast milk NICU put them on NeoSure. While they are both growing great from 2lbs 14oz/ 3lbs 14 oz to now 10 and 12 pounds at 1 month adjusted, it is SO expensive. The go through one 20$ can in 24 hours. I will continue to purchase as long as I am able, but I wish we received more coupons (we've only got one and they're almost 4 months old) or there was a multiples program. This also gives one of my boys terrible gas, but is controlled with gas drops.
Date published: 2019-07-01
Rated 5 out of 5 by from Wonderful product for our preemie baby This was a great product for our baby. I was able to pump for 2 months and supplemented with Neosure. When I stopped breastfeeding, we used Neosure only. We used it until she was 7 months old, and then switched to Similac Advance. We have had no problems at all.
Date published: 2019-06-19
Rated 5 out of 5 by from Miracle grow for humans My preemie was born at 33 weeks and we initially bottled breastmilk, then breastfeed but my milk dried out once he got out of the hospital. At first this made him colicky, gassy and constipated so we switched to lactose free (refused), soy (refused) and similac pro total comfort (painful gas with use of gas drops). We went back to neosure and prepared to use probiotics as well, however he adjusted fine and no longer colicky or constipated... This formula is helping him thrive and grow! Born 33 weeks ,4lbs 14oz but dropped to 4lbs and now 8 weeks, almost 8lbs!
Date published: 2019-06-16
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