Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months


Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch up.

Help support her development in the first full year by feeding her Similac NeoSure, a nutrient-enriched* formula for babies who were born prematurely.


Supports excellent growth during baby’s first year.1

  • Increased protein, energy, vitamins, and minerals compared to term infant formula
  • Extra calories for growth
  • Calcium and phosphorus for baby’s growing bones

Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula.1 Has OptiGRO to support your baby's brain and eye development.

Learn more about the nutritional needs of your preemie.

Get tips for keeping your baby’s immune system strong.

Learn why catch-up growth is important.

* Increased protein, vitamins, and minerals compared to term infant formula.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107:638-689.

Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

13.1-oz Powder

1-qt Ready to Feed

2-fl-oz Ready to Feed

For babies who were born prematurely

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
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Similac NeoSure Reviews

Rated 4 out of 5 by from Definitely pros and cons This formula is great for my 28 weeker, whom is now 6 months. We had slight consiptation (all babies get constipated) but this formula still works great. Super grateful except I really really wish they made a bigger can!!!!! I’ve heard excuses about “because kids don’t drink it for long” but that’s a lie. Since birth it was added calories to my BM but now it’s straight neosure and her pediatrician doesnt see us changing so it’s kind of a pain. And I wish the stores sold it in the box, it’s nice to get some from the NICU follow up and it have the 2$ coupon!
Date published: 2018-06-15
Rated 5 out of 5 by from Neosure is excellent boon for premature babies i had a premature baby boy who was born a month before the expected date. me and wife were so worried about the health of the baby during the time of the delivery. for our good, the baby was born healthy and was weighing 5.5 pounds which is less to the standard charts that are recommend. we met our pediatrician and raised our concern and she advised to give neosure starting the second monthly checkup. As my wife was also feeding and her milk was not completely enough we decided to do Neosure during morning and afternoon. Initially the baby has gas issues with neosure and we diluted the milk with more water to help him not to run into any digestion problems. We slowly increased from 2.5 FL to 3.5 FL. Sooner from third checkup, we saw excellent result in terms of baby hieght, weight and head circumference. He is also very active. i would highly recommend Neosure to premature babies and it will work wonders if we are cautious of how much dilution your baby should take. it would be nicer here if they allow to share the pics of the baby before and after the neosure consumption so we really see a pictorial difference:) Thanks Samilac for being another mom for my baby .
Date published: 2018-06-12
Rated 2 out of 5 by from Gas and discomfort My baby has been on Neosure since he was born at 4 pds. His doctor suggested the ready to feed neosure, which I didn't have any problems with. After a while I switched over to the powder and it seems like he's been extremely gassy and has started spitting up way more frequently. During night time hours he seems to grunt and whine as if he has an upset stomach. I'm currently looking for an alternative because it breaks my heart to see him moan in pain. This is a great product to help your baby gain weight, but I don't recommend keeping your baby on this formula very long.
Date published: 2018-06-07
Rated 5 out of 5 by from Great for my preemie twins! My twins were born at 31 weeks with an emergency c-section. My daughter was 3 lbs 15 oz and my son was 4 lbs 7 oz. Both of them were feed breastmilk with the NeoSure 22 cal powder to help them gain weight. My daughter came home after 5 weeks and my son after 7 weeks. My little girl still needs the NeoSure added to her Breastmilk to help her gain weight since she is in the bottom 5% on the growth chart. The formula can be found at all my local stores (Publix, Target, Walmart, BabiesRus), however, it is quite expensive.
Date published: 2018-06-04
Rated 4 out of 5 by from Great product, but impossible to find My daughter was born at 34 weeks and was in the nicu for 6 days. This formula helped her gain the weight she needed to come to home to us. The hospital had given us a few packages of the ready feed formula to bring home with us. My daughter drinks them with no problems. However, after searching 5 different stores and online, we could NOT find them anywhere! It was very frustrating!
Date published: 2018-06-03
Rated 3 out of 5 by from This product has pros and cons for sure I am in the club with everyone else, I have premature twin girls who were admitted into NICU at birth the nurses gave them the premade formula and it helped we even fortified my wifes BM but at home on 100% powder they experience intense gas pains and all night...they have irregular bowl movements now as well...its helping them....and not helping them
Date published: 2018-06-01
Rated 4 out of 5 by from Did wonders for my micro preemie!! My daughter is a micro preemie, she was born at just 23 weeks. That plus stress and a lack of skin to skin wreaked havoc on my milk supply. Neosure had to take its place, it did WONDERS!!! Definitely recommend, but does cause constipation.
Date published: 2018-05-29
Rated 4 out of 5 by from This product has pros and cons I've read some of the reviews to see what other moms are experiencing and I am not alone. My daughter was born at 32wks only weighing 3lbs 3ozs and Neosure has helped her grow wonderfully. She's now 8lbs 2ozs an 2 1/2 mos. My milk supply slowed down and I had to make the switch. Unfortunately it gives her terrible gas and she looks like she's in pain to pass a bowel movement. I was at first instructed to recipe a 55ml to 1 scoop ratio and an 80ml to 2 scoops in order for her to gain weight fast. It worked. She had a GI visit 3wks ago and I mentioned the gas constipation and they only suggested changing up to follow the recipe on the can to see if that would help, I have not seen any improvements so far. I thought well maybe she's lactose intolerant but they say she's too young to tell or have....I don't know what to do at this point. She'll be 3mos June 4th.
Date published: 2018-05-25
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