Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months

Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch-up.

Help support her development in the first full year by feeding her Similac NeoSure.

Has OptiGRO to support your baby's brain and eye development.

Learn more about the nutritional needs of your preemie.

newlook-logo Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

Similac NeoSure 13.1 oz formula with Iron for preemies 13.1-oz Powder

Similac NeoSure 13.1 oz formula with Iron for preemies 1-qt Ready to Feed

Similac NeoSure 13.1 oz formula with Iron for preemies 2-fl-oz Ready to Feed

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
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Rated 5 out of 5 by Awesome My daughter was born at 35 wks with a heart condition that makes it hard for her to gain weight. I breastfed her till 3 months and the stress from my mom passing and other events I dried up and couldn't produce. So we tried 3 different formulas before yours and they didn't work. As soon as we have her the Neosure she drank the whole bottle with out crying. She loves it and we are very happy that finally found one that also helps with her weight a little. October 18, 2016
Rated 4 out of 5 by Happy Babies = Happy Mommy Our preemie twins have been on Neosure since they were able to start feeding by NG tube. It's a great product for tiny tummies! October 14, 2016
Rated 4 out of 5 by Specialist Recommended My son was born at 36.5 weeks, however he was small for gestational age (SGA) at 4lbs 10oz so he was being supplemented with Neosure while in the NICU at the hospital for a week. Once he came home, he mostly received breastmilk for the first 3 months of his life with the occasional Neosure feeding (probably once every other day). The breastfeeding was just so convenient but now that I have had to return to work, he has every other feeding as Neosure and seems to be gaining weight at about a pound every 3 weeks. Our pediatrician is pleased with his growth and although he has a long way to go before "catching up" - he is below 5th percentile for weight and in the 15th percentile for height/length at 3 months old - he is still showing good growth so we are continuing with the pricey Neosure. I echo the comments from others about the price...on top of the hospital bills of having a preemie, buying this specific formula is very difficult on the budget. Note for other moms: The single feeds can be bought on -- we bought some of those to keep in the diaper bag for emergency situations where mommy brain results in no bottle prepared or not easily able to breastfeed. I'm all about the delivery to home too! October 10, 2016
Rated 4 out of 5 by Impressive weight a price My baby wasn't a preemie, she was only 10 days early and weighed 5lbs 15oz at birth. However, She dropped a pound the first day due to a few minor conditions, and has had difficulty gaining it back. The hospital ( she was in pediatrics an extra week) recommend supplementing. I had wanted to breastfeed exclusively, but she also had some trouble latching on, so we started supplementing with enfamil newborn. This formula gave her reflux and diarrhea when we switched from supplementing to all formula at about 3 weeks. She was then switched to gentlease which eliminated the digestive issues, but she was not gaining nearly enough weight. The pediatrician switched her to NeoSure. She is now gaining weight at an impressive rate. It seems like she has outgrown her NB size clothing overnight. But at what a price! Not only is NeoSure quite expensive, but it is also causing her terribly painful gas. Her stomach gets extremely bloated, and despite burping like "the Simpson's" Barney and passing horribly stinky gas, she remains bloated and in pain. We are trying gripe water rite now, so I hope it provides relief because the standard infant gas drops didn't. I am reluctant to change formulas again, and the weight gain has been just fantastic, but I don't know if the toll it takes on her little tummy is worth it. I wish Similac made an easy to digest preemie formula. Also, the quart size ready to use formula is very hard to find, and I didn't know it even came in single serving size until I looked on this website. I have been looking for it in all the local stores because I wind up having to dump a lot when I open a quart. The single serving size is soo extremely convenient, while the quart seems to defeat the purpose. The beauty of the ready to use formula is that it is shelf stable, but once opened, it of course, needs refrigeration, and when on the go, the larger bottle just winds up having to be thrown away, and it is so expensive. I would LOVE if the single serve size was more readily available, but I would really, REALLY LOVE it if u made the single serves in 8oz., since at 9weeks my daughter already takes 6-8oz per bottle and I intend to keep her on this formula for some time if the tummy issues can be managed. October 9, 2016
Rated 3 out of 5 by Caused terrible diaper rash My twins were born at 32 weeks 6 days and spent two weeks in NICU prior to coming home. While in NICU they received my pumped BM supplemented with Neosure, which we continued after discharge. After their demand exceeded my BM supply, which happened around 5-6 weeks, we began to supplement with Neosure. Suddenly they developed painful raw diaper rash which refused to heal. Pediatrician referred us to Similac Sensitive and the rash cleared up within 2 days. October 7, 2016
Rated 5 out of 5 by Proud Mom of a 24 weeker My daughter was born at 24 weeks and 4 days. She spent 85 days in the NICU. I was able to provide breast milk for her first 2 months. Then we had to supplement 50/50 with forumla for about a month with a different brand of formula that she had reflux with. About a week before she went home she was switched to Neosure when I could no longer produce milk. She was 5lbs 3oz when she went home and in the 10 to 15th percentile in weight. Now 2 months later on Neosure she weighs 11lbs 3oz and is in the 70 to 90th percentile and her pediatrician is thrilled with her weight gain and overall growth. The Neosure does give her a lot of gas but it doesn't aggravate her reflux. I would definitely recommend Neosure. October 5, 2016
Rated 3 out of 5 by Gassy gassy gassy. My 1lb 5oz preemie received breast milk fortified with Neosure until just this week when I was no longer able to provide breast milk. The Neosure makes her terribly gassy and I'm concerned that without breast milk that the gas may just not be worth sticking with the Neosure. It is recommended by our pediatrician, but if the gas is too much of a problem we will search for other solutions. October 4, 2016
Rated 4 out of 5 by Wish it was available in a larger size My twins were born at 32 weeks and 4 days and have been on this formula since being in the NICU. I wish that I was able to buy larger sizes as I have to feed two babies. One can does not last very long. I can order in bulk from Target or Amazon but then I can't use the $5 checks. It's very frustrating that all of the other types are available in larger containers or even in a generic brand except for this one. October 2, 2016
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