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Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months


Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch up. During her first full year, feed her Similac NeoSure, a nutrient-enriched formula for babies who were born prematurely, and help support her development.

Similac NeoSure is now available in a NEW value-size can, which provides over 70% more formula.*


Supports excellent growth during baby’s first year.1

  • Increased protein, energy, vitamins, and minerals compared to term infant formula
  • Extra calories for growth
  • Calcium and phosphorus for baby’s growing bones

Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula.1 Has OptiGRO® to support your baby's brain and eye development.

Learn more about the nutrition needs of your preemie.

Get tips for keeping your baby’s immune system strong.

Learn why catch-up growth is important.

* Versus NeoSure 13.1-oz powder.
† Increased protein, vitamins, and minerals compared to term infant formula.
‡ Compared to term infant formula.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107(4):683-689.

Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

22.8-oz Powder

13.1-oz Powder

1-qt Ready to Feed

2-fl-oz Ready to Feed

neosure-video NeoSure video

NoPalmOil-Video-2 No Palm Oil/Palm Olein Oil

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
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Similac NeoSure Reviews

Rated 4 out of 5 by from Great for my preemie Like many others my 34 weeker was placed on neosure in the nicu and has been in it since. It had helped my little one gain weight. The only downside is it is expensive and a little hard to find. You definitely need coupons!
Date published: 2021-01-08
Rated 4 out of 5 by from Neo Sure Similac Review I concur with the majority of the mother's on here. My baby boy was born at 36weeks and he was quickly positioned on Neosure. My child is gassy piece it has assisted him with developing. I additionally think this formula is over the expensive yet it's the lone recipe he has been on since birth. it's elusive and the stores run out so quick yet it's so costly y. I need coupons to assist with the expense. I would give four star as it is little expensive.
Date published: 2020-12-23
Rated 5 out of 5 by from Amazing formula, best when paired with Mylicon We started our 33 week old preemie on neosure while still in the NICU to supplement my breast milk. He gained 2lbs in the first month and 3lbs in the second month. The pediatrician recommended the use of mylicon by adding drops to the formula. He burps and passes gas easily and has daily bowel movements. He also sleeps very well. We are so grateful! As others have said, it is hard to find and is very expensive.
Date published: 2020-12-15
Rated 5 out of 5 by from Awesome product for my 24 weeker I had my daughter at 24 weeks she was born only 1lb and 10.5in and I struggled terribly with producing milk and that’s when we started her on neosure and I swear this is the best thing ever! She’s gone from 1lb to 14lb and is currently 24in at a little over a year old. It’s definitely a little expensive but it’s worth it so Thank you guys so much for all you do and for providing for our most precious miracles!
Date published: 2020-12-04
Rated 5 out of 5 by from Best Baby Food Ever for Preemie Babies My daughter was born at 35 weeks and only weighed 4 lb 9 oz at birth. My milk didn't come in at all for the first three days and she was given neosure to help her gain weight and get stronger in the nicu. My breast milk supply was never great and by the time she was released from the nicu I couldn't keep up with pumping the amount she needed to eat. After 4 months I wasn't able to produce anymore breast milk. So my baby has mostly been on Neosure for her first 9 months of life. She is thriving now! They don't even factor her preemie age when doing her growth charts anymore and she is in the 48th percentile for weight, the 65th percentile for head circumference and the 94th percentile for height!!! She loves her formula and she does great with it. She has never been very gassy, she doesn't throw up or have an upset stomach. This formula really is just amazing.
Date published: 2020-09-08
Rated 5 out of 5 by from Awesome product that helped my 34 week baby gain her weight. This product was given to my 34 week baby girl and helped her gain weight from the start. I do give credit for her quick weight gain and able to come home after 10 days in the NICU. She loved the formula and never had any issues with the formula. She is now 7 months and she's a very healthy, happy and thriving well.
Date published: 2020-08-20
Rated 4 out of 5 by from Preemie Baby My sweet babe was born at 36 weeks gestation and spent quite a bit of time in the NICU. The doctors had her on my breast milk with Neosure mixed in it until recently, now we are just doing Neosure. My baby loves her “protein drinks” and it has helped her get onto the weight charts in her first year. The only reason I didn’t give it 5 stars is because it does give her some gas but she’s finally figured out how to get rid of that.
Date published: 2020-08-11
Rated 5 out of 5 by from Great results My baby was born at 23 weeks. His weight at the time 1 pound 12 oz. he is now 9 months or 5 months corrected age and weighs 17 pounds. We have been happy with his development. Yes, he is gassy, but I was also given some gas drops and his bowel movement is slow at time but I was given some suppositories for that as well. When we left NICU he was on the ready to feed formula and was advised at high risk clinic to continue with the ready to feed option. It has been expensive but totally worth it.
Date published: 2020-08-10
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