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Similac® NeoSure®

Promotes catch-up growth during your premature baby’s first 12 months


Your premature baby didn’t get her full 9 months in the womb, so her body is working hard to catch up. During her first full year, feed her Similac NeoSure, a nutrient-enriched formula for babies who were born prematurely, and help support her development.

Similac NeoSure is now available in a NEW value-size can, which provides over 70% more formula.*


Supports excellent growth during baby’s first year.1

  • Increased protein, energy, vitamins, and minerals compared to term infant formula
  • Extra calories for growth
  • Calcium and phosphorus for baby’s growing bones

Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula.1 Has OptiGRO® to support your baby's brain and eye development.

Learn more about the nutrition needs of your preemie.

Get tips for keeping your baby’s immune system strong.

Learn why catch-up growth is important.

* Versus NeoSure 13.1-oz powder.
† Increased protein, vitamins, and minerals compared to term infant formula.
‡ Compared to term infant formula.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107(4):683-689.

Similac NeoSure 13.1 oz formula with Iron for preemies

Available In:

22.8-oz Powder

13.1-oz Powder

1-qt Ready to Feed

2-fl-oz Ready to Feed

neosure-video NeoSure video

NoPalmOil-Video-2 No Palm Oil/Palm Olein Oil

Nutrition Information

Powder / 13.1 oz

Serving size: 100 Cal (4.5 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac NeoSure
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Similac NeoSure Reviews

Rated 5 out of 5 by from Best Baby Food Ever for Preemie Babies My daughter was born at 35 weeks and only weighed 4 lb 9 oz at birth. My milk didn't come in at all for the first three days and she was given neosure to help her gain weight and get stronger in the nicu. My breast milk supply was never great and by the time she was released from the nicu I couldn't keep up with pumping the amount she needed to eat. After 4 months I wasn't able to produce anymore breast milk. So my baby has mostly been on Neosure for her first 9 months of life. She is thriving now! They don't even factor her preemie age when doing her growth charts anymore and she is in the 48th percentile for weight, the 65th percentile for head circumference and the 94th percentile for height!!! She loves her formula and she does great with it. She has never been very gassy, she doesn't throw up or have an upset stomach. This formula really is just amazing.
Date published: 2020-09-08
Rated 5 out of 5 by from Awesome product that helped my 34 week baby gain her weight. This product was given to my 34 week baby girl and helped her gain weight from the start. I do give credit for her quick weight gain and able to come home after 10 days in the NICU. She loved the formula and never had any issues with the formula. She is now 7 months and she's a very healthy, happy and thriving well.
Date published: 2020-08-20
Rated 4 out of 5 by from Preemie Baby My sweet babe was born at 36 weeks gestation and spent quite a bit of time in the NICU. The doctors had her on my breast milk with Neosure mixed in it until recently, now we are just doing Neosure. My baby loves her “protein drinks” and it has helped her get onto the weight charts in her first year. The only reason I didn’t give it 5 stars is because it does give her some gas but she’s finally figured out how to get rid of that.
Date published: 2020-08-11
Rated 5 out of 5 by from Great results My baby was born at 23 weeks. His weight at the time 1 pound 12 oz. he is now 9 months or 5 months corrected age and weighs 17 pounds. We have been happy with his development. Yes, he is gassy, but I was also given some gas drops and his bowel movement is slow at time but I was given some suppositories for that as well. When we left NICU he was on the ready to feed formula and was advised at high risk clinic to continue with the ready to feed option. It has been expensive but totally worth it.
Date published: 2020-08-10
Rated 3 out of 5 by from If my sons doctor did not recommend it I wouldn’t buy this I do not like this milk. It gives my baby terrible gas every feeding. He can’t sleep and I have to use gas drops. I wish I could switch to something else. It’s frustrating.
Date published: 2020-08-07
Rated 4 out of 5 by from Great Formula with some side effects I agree with most of the mom's on here. My baby girl was born at 34weeks and was immediately placed on Neosure. My baby is very gassy bit it has helped her grow tremendously. I also think this formula is very expensive but it's the only formula she has been on since birth. With Covid cases consistently rising, it's hard to find and the stores run out so fast but it's so expensive you can't buy 4 or 5 quarts/cans at a time. I need coupons, vouchers, or something to help with the cost.
Date published: 2020-08-07
Rated 5 out of 5 by from Great for my 6 week early son Helped him gain the weight he needed to leave the NICU after 6 days and come home
Date published: 2020-07-01
Rated 5 out of 5 by from Both my babies have used/ currently using this formula Both my children have needed this formula. I love it. It has helped my son put back his birth weight and then some already. He was born 35 weeks 4 days. And my daughter has exceeded expectations and is currently a healthy and brilliant 4 year old.
Date published: 2020-06-21
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