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Similac

Similac Pro-Total Comfort*

Our most gentle formula with 2’-FL HMO for immune support.

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Similac® Pro-Total Comfort™ Easy-to-digest Infant Formula

Available In:

Similac® Pro‐Total Comfort 1.41-lb Powder

similac-immunity-OLV.jpg Similac Infant Formula for Immune Support

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NoPalmOil-Video-1 Similac It All adds Up

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Switching formulas due to a baby’s sensitive tummy can be overwhelming. At Similac®, we promise to support you on your journey of nourishing your baby and her unique nutrition needs.

The Similac Pro-Total Comfort Difference

  • Our most gentle formula with 2’-FL HMO for immune support and our unique blend of DHA and Lutein for brain and eye development
  • Parents reported a significant reduction in fussiness, gassiness, and crying after just 1 day of feeding
  • Partially hydrolyzed protein for easy digestion
  • No artificial growth hormonesǁ
  • Makes 4 more 6-fl-oz bottles vs Enfamil NeuroPro Gentlease®¶
  • Gentle for supplementing

See the difference for yourself in our new video.

Gentle formula with partially hydrolyzed protein

Similac Pro-Total Comfort is the first gentle formula with partially hydrolyzed protein and 2’-FL Human Milk Oligosaccharide (HMO),# an immune-nourishing prebiotic like that found** in breast milk. HMOs feed good bacteria in the gut, where 70% of the immune system exists. Similac with 2’-FL HMO helps strengthen baby’s immune system to be more like the breastfed infant than ever before.

 

Designed for delicate tummies

Similac Pro-Total Comfort with 2’FL HMO is an easy-to-digest, gentle formula that’s designed for delicate tummies. It’s a good choice if your child has difficulty tolerating other milk-based formulas.

Exclusive blend of nutrients

Our exclusive blend has DHA, Lutein, and Vitamin E—important ingredients found in breast milk. DHA supports brain development, Lutein supports eye health, and Vitamin E is an important nutrient that supports developing cells.

For More Support and Information, Join Similac® StrongMoms®

Get tips on feeding, nutrition, baby development, and more when you join. Sign up is fast, free, and easy.

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* Not for infants or children with galactosemia.
After switching to Pro-Total Comfort.
ǁ No significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows.
Similac Pro-Total Comfort 1.41-lb pack vs Enfamil NeuroPro Gentlease 1.25-lb pack.
# Not from human milk.
** At significant levels.
Enfamil NeuroPro Gentlease is not a registered trademark of Abbott Laboratories.

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Similac® Pro-Total Comfort™ Easy-to-digest Infant Formula

Available In:

Similac® Pro‐Total Comfort 1.41-lb Powder

similac-immunity-OLV.jpg Similac Infant Formula for Immune Support

NoPalmOil-Video-1 No Palm Oil/Palm Olein Oil

NoPalmOil-Video-1 Similac It All adds Up

NoPalmOil-Video-1 All in One Day

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Nutrition Information

Powder / 1.45 lb

Serving size: 100 Cal (5 fl oz, prepared as directed)

Amount per serving

  • Calories:

    100

  • Volume, mL:

    148

  • Protein, g:

    2.32

  • Fat, g:

    5.4

  • Carbohydrate, g:

    10.7

  • Water, g:

    133

  • Linoleic Acid, mg:

    1000

Vitamins & Minerals

Similac Advance Stage 1

FAQs

What is the difference between Similac Pro-Total Comfort vs Similac Pro-Sensitive®?

Similac Pro-Sensitive has intact milk protein while Similac Pro-Total Comfort has 100% whey protein that is partially hydrolyzed as an alternative to standard intact-protein, milk-based formulas.

What’s the difference between Similac Pro‐Advance®, Similac Pro‐Sensitive, Similac Pro-Total Comfort, and other Similac baby formulas?

Similac Pro‐Advance is our closest formula to breast milk. Similac Pro‐Advance, Similac Pro‐Sensitive and Similac Pro-Total Comfort now have 2’-FL HMO (Human Milk Oligosaccharide*), a unique immune-nourishing prebiotic. Other Similac baby formulas also provide complete nutrition for babies, but it’s up to parents, along with their doctor, to choose which formula to feed their baby.

* Not from human milk.

What does Similac Pro-Total Comfort help with?

Similac Pro-Total Comfort with 2’-FL HMO is an easy-to-digest, gentle baby formula that’s designed for babies who have difficulty tolerating other milk-based formulas.

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Similac® Pro-Total Comfort Reviews

Rated 3 out of 5 by from Works fine, but is the WORST to deal with. My babe has no issues taking this formula. No constipation. He tolerates it fine. HOWEVER... This is so hard to dissolve and foams up SOOOO BAAAAD when you try to shake it or mix. Like, I'm about to the point of saying screw this and going back to Enspire (which is more expensive) just because I don't have to fight to get the crap to dissolve. Warm water doesn't work. Stirring with a fork doesn't work. The only thing that eradicates the bubbles is gas medicine, but that still doesn't completely dissolve it. It's extremely frustrating.
Date published: 2021-01-20
Rated 1 out of 5 by from Too Bubbly Too many bubbles and it takes forever to pop even when I let it sits, there’s still a whole lot of bubbles plus this formula smells, it gives my baby a bad breath.
Date published: 2021-01-17
Rated 2 out of 5 by from Clumpy/foamy This formula doesn’t mix well at all. Its very foamy & clumps up at the bottom. You have to vigorously shake the bottle to mix it!! Still yellow clumps at the bottom!!!
Date published: 2021-01-17
Rated 2 out of 5 by from Beware air bubbles! I was so excited to try this formula with my 2 week old! She doesn’t seem to do so well with my breast milk, she gets very gassy. So I switch between breast milk and formula. While feeding my baby I noticed an absurd amount of air bubbles in the formula that I didnt see with the pro sensitive. She was up all night with gas pains and gripe water or gas drops didn’t seem to help. If you try this formula, try it anti-colic bottles, or if your baby isn’t very gassy. I am so disappointed :(
Date published: 2021-01-10
Rated 4 out of 5 by from 3rd times a charm! After a smooth month on the Similac Pro Advance, my baby started fussing on the bottle and limiting how much she ate. I switched to Pro Sensitive and saw the same thing, and then switched to Pro Total Comfort after doing some research. She's much happier, less gassy, and drinking calmly. I'm so happy I found this - though I did discard about a full container between the pro advance and sensitive during transitions.
Date published: 2021-01-07
Rated 1 out of 5 by from Didn't work for my son My son was 5 weeks premature (4wks old now) and had moderate acid reflux on the Similac Pro-Advanced, so we switched to the Pro-Total Comfort. After the first couple of feedings, we noticed the reflux, spitting up, and gas were significantly worse. He also is now having "blow out" bowel movements. Also, the formula smells oddly like cheese.
Date published: 2021-01-07
Rated 5 out of 5 by from Ready to feed I love this formula but I wish they had the ready to feed on the go bottles or big bottles. I buy the newborn ones when I can find them but she’s up to four ounces now. I just use it to supplement breastfeeding but she does really well on this. I also use the pro-sensitive when I can’t find this.
Date published: 2021-01-03
Rated 5 out of 5 by from LOVE IT!!! Love this milk my son has been using this milk since birth.
Date published: 2020-12-27
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