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Similac

Similac Pro-Total Comfort*

Our most gentle formula with 2’-FL HMO for immune support.

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Similac® Pro-Total Comfort™ Easy-to-digest Infant Formula

Available In:

Similac® Pro‐Total Comfort 1.41-lb Powder

NoPalmOil-Video-1 No Palm Oil/Palm Olein Oil

NoPalmOil-Video-1 Similac It All adds Up

NoPalmOil-Video-1 All in One Day

 

Switching formulas due to a baby’s sensitive tummy can be overwhelming. At Similac®, we promise to support you on your journey of nourishing your baby and her unique nutrition needs.

The Similac Pro-Total Comfort Difference

  • Our most gentle formula with 2’-FL HMO for immune support and our unique blend of DHA and Lutein for brain and eye development
  • 1 Day—less crying, less fussiness, and less gas§
  • Partially hydrolyzed protein for easy digestion
  • No artificial growth hormonesǁ
  • Makes 4 more 6-fl-oz bottles vs Enfamil NeuroPro Gentlease®¶

See the difference for yourself in our new video.

Gentle formula with partially hydrolyzed protein

Similac Pro-Total Comfort is the first gentle formula with partially hydrolyzed protein and 2’-FL Human Milk Oligosaccharide (HMO),# an immune-nourishing prebiotic like that found** in breast milk. HMOs feed good bacteria in the gut, where 70% of the immune system exists. Similac with 2’-FL HMO helps strengthen baby’s immune system to be more like the breastfed infant than ever before.

 

Parents reported a significant reduction in fussiness, gassiness, and crying after just 1 day of feeding.

Designed for delicate tummies

Similac Pro-Total Comfort with 2’FL HMO is an easy-to-digest, gentle formula that’s designed for delicate tummies. It’s a good choice if your child has difficulty tolerating other milk-based formulas.

Exclusive blend of nutrients

Our exclusive blend has DHA, Lutein, and Vitamin E—important ingredients found in breast milk. DHA supports brain development, Lutein supports eye health, and Vitamin E is an important nutrient that supports developing cells.

For More Support and Information, Join Similac® StrongMoms®

Get tips on feeding, nutrition, baby development, and more when you join. Sign up is fast, free, and easy.

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* Not for infants or children with galactosemia.
After switching to Pro-Total Comfort.
§ Parents reported‡ a significant reduction in fussiness, gassiness, and crying after 1 day.
ǁ No significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows.
Similac Pro-Total Comfort 1.41-lb pack vs Enfamil NeuroPro Gentlease 1.25-lb pack.
# Not from human milk.
** At significant levels.
Enfamil NeuroPro Gentlease is not a registered trademark of Abbott Laboratories.

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Similac® Pro-Total Comfort™ Easy-to-digest Infant Formula

Available In:

Similac® Pro‐Total Comfort 1.41-lb Powder

NoPalmOil-Video-1 No Palm Oil/Palm Olein Oil

NoPalmOil-Video-1 Similac It All adds Up

NoPalmOil-Video-1 All in One Day

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Nutrition Information

Powder / 1.45 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:

    100

  • Volume, mL:

    156

  • Protein, g:

    2.32

  • Fat, g:

    5.4

  • Carbohydrate, g:

    11

  • Water, g:

    141

  • Linoleic Acid, mg:

    1000

Vitamins & Minerals

Similac Advance Stage 1

FAQs

What is the difference between Similac Pro-Total Comfort vs Similac Pro-Sensitive®?

Similac Pro-Sensitive has intact milk protein while Similac Pro-Total Comfort has 100% whey protein that is partially hydrolyzed as an alternative to standard intact-protein, milk-based formulas.

What’s the difference between Similac Pro‐Advance®, Similac Pro‐Sensitive, Similac Pro-Total Comfort, and other Similac baby formulas?

Similac Pro‐Advance is our closest formula to breast milk. Similac Pro‐Advance, Similac Pro‐Sensitive and Similac Pro-Total Comfort now have 2’-FL HMO (Human Milk Oligosaccharide*), a unique immune-nourishing prebiotic. Other Similac baby formulas also provide complete nutrition for babies, but it’s up to parents, along with their doctor, to choose which formula to feed their baby.

* Not from human milk.

What does Similac Pro-Total Comfort help with?

Similac Pro-Total Comfort with 2’-FL HMO is an easy-to-digest, gentle baby formula that’s designed for babies who have difficulty tolerating other milk-based formulas.

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New Moms

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  • Up to $400* in savings
  • Information about your baby’s milestones
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Similac® Pro-Total Comfort Reviews

Rated 5 out of 5 by from Fussy & Gassy on all other formulas My baby was gassy, fussy, and uncomfortable on all other formulas including other similac product. This is the ONLY formula I have found to keep him happy. We love this product!
Date published: 2020-05-28
Rated 2 out of 5 by from Makes my baby automatically cry after every feeding I chose this product because it says it’s for delicate tummies but my 2 weeks old automatically cries after every feeding
Date published: 2020-05-22
Rated 5 out of 5 by from Works SO good for fussiness!!!!! I don’t typically take the time to write reviews on any products, but we’ve had such a great experience with this product that I can’t help but to mention it! Our son had been fussing and crying around the clock, pretty much if he was awake then he was upset. We started this pro-total comfort formula and literally the very next day a complete turn around!!! No fussiness or crying all day (unless he was hungry of course). But as new first time parents we’re trying to learn what makes our baby happy and comfortable, and this formula most definitely has! I’m so grateful we found a formula that keeps our baby happy and I highly recommend this formula!
Date published: 2020-05-01
Rated 1 out of 5 by from My Experience Baby is the most uncomfortable she’s ever been on this formula.
Date published: 2020-04-16
Rated 4 out of 5 by from Great formula for sensitive tummies Great for babies that are intolerant for other milk formulas I totally recommend
Date published: 2020-04-04
Rated 4 out of 5 by from Works great wish there was a ready made option! We love this product and it does well for our son who had very bad gas issues. My only complaint is I wish it came in the large ready mix bottle. We were able to get several of the 2 oz ready mix bottles from the hospital and those a great for when we are away from home and he needs a feeding. We had hoped we could provide our daycare provider with a ready made bottle but I haven't been able to find this type available.
Date published: 2020-04-01
Rated 5 out of 5 by from Happy Baby, Happy Momma! We struggled with fussiness, gas, and constipation. We tired Pro-Advance then Sensitive and nothing! The thought of us having to help our baby have a BM was starting to worry me. I kept thinking he was getting dependent on us. After 24 hours on this formula, we have a whole different baby!! We noticed he wasn't fussy, while feeding he wasn't gassy as usual, and he already has had 2 dirty diapers with no help from us!! Strongly recommend this formula if your baby is experiencing any of the symptoms described above!! This formula is really a game changer, and so far baby enjoys it!! Happy baby, Happy momma!!!
Date published: 2020-03-11
Rated 5 out of 5 by from Game changer! We changed to total comfort and went from literally never sleeping to sleeping 6 hour stretches at night and taking naps during the day! This formula changed all of our lives for the better and we have a much happier baby! He never had gas issues but we could tell he was uncomfortable so we made the switch and after the first day we saw a huge improvement!
Date published: 2020-02-13
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