COVID-19 Update: To learn more about our promise to parents during this time, and for a list of direct-ship retailers, Click Here

Similac

Similac Pro-Total Comfort*

Our most gentle formula with 2’-FL HMO for immune support.

ptccmodule-image
Similac® Pro-Total Comfort™ Easy-to-digest Infant Formula

Available In:

Similac® Pro‐Total Comfort 1.41-lb Powder

similac-immunity-OLV.jpg Similac Infant Formula for Immune Support

NoPalmOil-Video-1 No Palm Oil/Palm Olein Oil

NoPalmOil-Video-1 Similac It All adds Up

NoPalmOil-Video-1 All in One Day

 

Switching formulas due to a baby’s sensitive tummy can be overwhelming. At Similac®, we promise to support you on your journey of nourishing your baby and her unique nutrition needs.

The Similac Pro-Total Comfort Difference

  • Our most gentle formula with 2’-FL HMO for immune support and our unique blend of DHA and Lutein for brain and eye development
  • Parents reported a significant reduction in fussiness, gassiness, and crying after just 1 day of feeding
  • Partially hydrolyzed protein for easy digestion
  • No artificial growth hormonesǁ
  • Makes 4 more 6-fl-oz bottles vs Enfamil NeuroPro Gentlease®¶
  • Gentle for supplementing

See the difference for yourself in our new video.

Gentle formula with partially hydrolyzed protein

Similac Pro-Total Comfort is the first gentle formula with partially hydrolyzed protein and 2’-FL Human Milk Oligosaccharide (HMO),# an immune-nourishing prebiotic like that found** in breast milk. HMOs feed good bacteria in the gut, where 70% of the immune system exists. Similac with 2’-FL HMO helps strengthen baby’s immune system to be more like the breastfed infant than ever before.

 

Designed for delicate tummies

Similac Pro-Total Comfort with 2’FL HMO is an easy-to-digest, gentle formula that’s designed for delicate tummies. It’s a good choice if your child has difficulty tolerating other milk-based formulas.

Exclusive blend of nutrients

Our exclusive blend has DHA, Lutein, and Vitamin E—important ingredients found in breast milk. DHA supports brain development, Lutein supports eye health, and Vitamin E is an important nutrient that supports developing cells.

For More Support and Information, Join Similac® StrongMoms®

Get tips on feeding, nutrition, baby development, and more when you join. Sign up is fast, free, and easy.

ptc-difference-headerptc-difference-header
ptc-difference-module-1ptc-difference-module-2ptc-difference-module-3ptc-difference-module-4

* Not for infants or children with galactosemia.
After switching to Pro-Total Comfort.
ǁ No significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows.
Similac Pro-Total Comfort 1.41-lb pack vs Enfamil NeuroPro Gentlease 1.25-lb pack.
# Not from human milk.
** At significant levels.
Enfamil NeuroPro Gentlease is not a registered trademark of Abbott Laboratories.

ptc bugptc newlook
Similac® Pro-Total Comfort™ Easy-to-digest Infant Formula

Available In:

Similac® Pro‐Total Comfort 1.41-lb Powder

similac-immunity-OLV.jpg Similac Infant Formula for Immune Support

NoPalmOil-Video-1 No Palm Oil/Palm Olein Oil

NoPalmOil-Video-1 Similac It All adds Up

NoPalmOil-Video-1 All in One Day

ptc-productmodule-image
ptc-productbug-image
newlook-pro-totalcomfort

Nutrition Information

Powder / 1.45 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:

    100

  • Volume, mL:

    156

  • Protein, g:

    2.32

  • Fat, g:

    5.4

  • Carbohydrate, g:

    11

  • Water, g:

    141

  • Linoleic Acid, mg:

    1000

Vitamins & Minerals

Similac Advance Stage 1

FAQs

What is the difference between Similac Pro-Total Comfort vs Similac Pro-Sensitive®?

Similac Pro-Sensitive has intact milk protein while Similac Pro-Total Comfort has 100% whey protein that is partially hydrolyzed as an alternative to standard intact-protein, milk-based formulas.

What’s the difference between Similac Pro‐Advance®, Similac Pro‐Sensitive, Similac Pro-Total Comfort, and other Similac baby formulas?

Similac Pro‐Advance is our closest formula to breast milk. Similac Pro‐Advance, Similac Pro‐Sensitive and Similac Pro-Total Comfort now have 2’-FL HMO (Human Milk Oligosaccharide*), a unique immune-nourishing prebiotic. Other Similac baby formulas also provide complete nutrition for babies, but it’s up to parents, along with their doctor, to choose which formula to feed their baby.

* Not from human milk.

What does Similac Pro-Total Comfort help with?

Similac Pro-Total Comfort with 2’-FL HMO is an easy-to-digest, gentle baby formula that’s designed for babies who have difficulty tolerating other milk-based formulas.

AltBrandLogo

New Moms

Join today. Get the promise of Similac® StrongMoms® Rewards and:
  • Up to $400* in savings
  • Information about your baby’s milestones
Strongmom Decor Dsk
SIGN UP/SIGN IN * Offers may vary.

Similac® Pro-Total Comfort Reviews

Rated 5 out of 5 by from Only formula my baby can have without discomfort I am raising my grandson. He is entitled to WIC supplied formula, but can not tolerate any of their available formula (Gerber and Enfamil). Thankfully we can afford to buy him formula as the Total Pro Comfort is the only one we've found that he tolerates without colic and fussiness.
Date published: 2020-08-03
Rated 1 out of 5 by from Made baby more gassy My doctor recommended I try Pro-Total comfort after using Similac Pro-Advance for two weeks and my son started getting fussy, constipated and spitting up. Two days on Pro-Total Comfort and my son is screaming after every feeding, This made him more gassy than he ever was. He will try to sleep and wake up screaming burping and farting.
Date published: 2020-07-08
Rated 5 out of 5 by from Happy Baby! Happy Momma! I started alternating my breast milk supply with formula as well and I have one happy baby! Thankfully she has not had any issues. She is officially 1 month old and slept 5.5 hours last night! Thank you Similac! My only concern is that I can’t find coupons on line to help with the costs of buying the formula! But overall highly recommend
Date published: 2020-06-30
Rated 1 out of 5 by from Only made my baby fuss and scream My 5-week old was so calm and so easy going. Once we switched to this formula, after every feeding, she became horribly fussy and would scream almost nonstop. This formula was the opposite of comfort for her. I will never buy this product again. There is no reason a formula should hurt a baby this much. I cannot begin to understand what is so different from regular similac to this kind that makes a normal, happy baby turn into a colicky, fussy baby.
Date published: 2020-06-21
Rated 5 out of 5 by from Fussy & Gassy on all other formulas My baby was gassy, fussy, and uncomfortable on all other formulas including other similac product. This is the ONLY formula I have found to keep him happy. We love this product!
Date published: 2020-05-28
Rated 2 out of 5 by from Makes my baby automatically cry after every feeding I chose this product because it says it’s for delicate tummies but my 2 weeks old automatically cries after every feeding
Date published: 2020-05-22
Rated 5 out of 5 by from Works SO good for fussiness!!!!! I don’t typically take the time to write reviews on any products, but we’ve had such a great experience with this product that I can’t help but to mention it! Our son had been fussing and crying around the clock, pretty much if he was awake then he was upset. We started this pro-total comfort formula and literally the very next day a complete turn around!!! No fussiness or crying all day (unless he was hungry of course). But as new first time parents we’re trying to learn what makes our baby happy and comfortable, and this formula most definitely has! I’m so grateful we found a formula that keeps our baby happy and I highly recommend this formula!
Date published: 2020-05-01
Rated 1 out of 5 by from My Experience Baby is the most uncomfortable she’s ever been on this formula.
Date published: 2020-04-16
  • y_2020, m_8, d_11, h_16
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.10
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_680
  • loc_en_US, sid_sim-prod-900, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING), SortEntry(order=FEATURED, direction=DESCENDING)]
  • clientName_similac
  • bvseo_sdk, net_sdk, 2.3.0.0
  • CLOUD, getReviews, 32ms
  • REVIEWS, PRODUCT
close-btn