Similac® For Spit-Up NON‑GMO*,†

For less frequent spit-up in healthy infants

Trust Similac For Spit-Up to give your baby the nutrition she needs.

Clinically shown to reduce frequent spit-up by 54%.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants and children with galactosemia.
Among healthy 2-month-old infants, compared to standard milk-based formula. Lasekan JB et al. J Am Coll Nutr. 2014;33:136-146.

NON-GMO Similac baby formula for reducing spit-up.

Available In:

1.41-lb Powder

For spit-up in healthy infants

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac® For Spit-Up
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Similac For Spit-Up NON‑GMO Reviews

Rated 5 out of 5 by from Excellent product My baby is 4 months now and we been using this products for 2 months .. she wasn’t able to hold nothing on her tummy and we tried this product and it was like magic.. it was such a change ..
Date published: 2019-08-25
Rated 2 out of 5 by from Made Spit Up Worse We have went from Pro Advance to Sensitive to Nutramigen back to Sensitive to Similac for Spit Up. Spit up started getting worse after Similac for Spit Up and my son seemed grumpy. I’d rather deal with spit up then have a grumpy baby. Going back to Sensitive and dealing with it
Date published: 2019-08-24
Rated 4 out of 5 by from Semi helpful My pediatrician recommended this for my 6w old. She didn't spit up much but had silent reflux, and was just miserable. She isn't as miserable now, and doesn't have the reflux, but she is SO GASSY. and she barely poops now! I'm going to talk to the doctor again about switching to a different Similac, cuz poor little one is miserable farting ALL day lol. The product did what it said tho! And yes it clogged all my doctor brown bottles and nipples, I have to use Philips Avent bottles size 2 nipple for her to drink it. It's a little fast coming out but she handles it. Any other bottle clogs real bad idk why. And it is rather foamy maybe that is causing the gas?? But I still will always recommend Similac!
Date published: 2019-07-18
Rated 1 out of 5 by from This product is bad It is allll foam.. i was wondering why my son wasn't drinking it. There was nothing coming out of his bottle so i decided to chek and even if i squeeze the nipple nothing comes out its all foam.
Date published: 2019-06-24
Rated 5 out of 5 by from Best thing I found I can not believe my pediatrician did not know about this product to recommend. We tried so many other formulas before this one and the same constant spit up happened. My baby was healthy but kept spiting up Brest milk all the formulas we tried. And we were all just tired of doing laundry three times a day. Untill my husband happened to come across this Similac for spit up at a Walmart and decided to grab it. Thank you so much for this product it has saved us so much grief and my baby is actually feeding regularly now instead of every 10 minutes.
Date published: 2019-06-20
Rated 5 out of 5 by from This product works! Son had spit up issues at one month of age, switched to this and hasn’t had the issue since. Would love on the go bottles or packs though!
Date published: 2019-06-13
Rated 5 out of 5 by from Want bigger cans!! We love this product. Please make bigger cans!!!
Date published: 2019-05-27
Rated 4 out of 5 by from Mixed Results My LO has had severe acid reflux since birth and the Dr recommend we use Similac For Spit Up. I think overall it did help out for the first month and a half or so but for the last few weeks we’ve been battling with her spitting up WAY more then normal and now constipation also. I mix the formula per mfg instructions and shake each bottle to the point where my arms hurt and she still spits up clumps at times. Overall I would say that without this formula my LO would probably have a lot worse spit up and acid reflux. All though I know it’ll never happen I do wish it would work 100% of the time
Date published: 2019-05-27
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