Similac® For Spit-Up NON‑GMO*,†

For less frequent spit-up in healthy infants

Trust Similac For Spit-Up to give your baby the nutrition she needs.

Clinically shown to reduce frequent spit-up by 54%.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants and children with galactosemia.
Among healthy 2-month-old infants, compared to standard milk-based formula. Lasekan JB et al. J Am Coll Nutr. 2014;33:136-146.

NON-GMO Similac baby formula for reducing spit-up.

Available In:

1.41-lb Powder

For spit-up in healthy infants

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac® For Spit-Up
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Similac For Spit-Up NON‑GMO Reviews

Rated 5 out of 5 by from This formula is a blessing! From birth my baby started on Similac Pro-Advanced and she was constantly spitting it up. She was switched to Similac for Spit-up while we were still in the hospital. After a few feedings she had stopped spitting up. I'm extremely thankful for this formula! Thank you!!
Date published: 2019-11-20
Rated 5 out of 5 by from Love it My son was on advance similac & he kept crying for 3 days & spitting up and hardly drinking his whole 4oz took him to his dr today & she switched his formula. Wow my son is drinking his whole bottle now(4oz) . Not every 5/10 min like he was doing those three last days with the advance !!! & he’s so calm now sleeping peacefully. It also isn’t foam. Mines doesn’t even have that
Date published: 2019-10-11
Rated 3 out of 5 by from On the fence about this product I'm not sure how I feel about this formula.My little one is still spitting up and now seems like he is constipated.we have gone from ok m neosure to sensitive to alimentum and now this only plus is the smell is ten times better then the alimentum.I just hope we soon find the right formula for my little one that helps with is reflux and doesn't cause other issues.I also dont like that I cant find ready to feed or on the go in this formula.
Date published: 2019-10-01
Rated 5 out of 5 by from Excellent product My baby is 4 months now and we been using this products for 2 months .. she wasn’t able to hold nothing on her tummy and we tried this product and it was like magic.. it was such a change ..
Date published: 2019-08-25
Rated 2 out of 5 by from Made Spit Up Worse We have went from Pro Advance to Sensitive to Nutramigen back to Sensitive to Similac for Spit Up. Spit up started getting worse after Similac for Spit Up and my son seemed grumpy. I’d rather deal with spit up then have a grumpy baby. Going back to Sensitive and dealing with it
Date published: 2019-08-24
Rated 4 out of 5 by from Semi helpful My pediatrician recommended this for my 6w old. She didn't spit up much but had silent reflux, and was just miserable. She isn't as miserable now, and doesn't have the reflux, but she is SO GASSY. and she barely poops now! I'm going to talk to the doctor again about switching to a different Similac, cuz poor little one is miserable farting ALL day lol. The product did what it said tho! And yes it clogged all my doctor brown bottles and nipples, I have to use Philips Avent bottles size 2 nipple for her to drink it. It's a little fast coming out but she handles it. Any other bottle clogs real bad idk why. And it is rather foamy maybe that is causing the gas?? But I still will always recommend Similac!
Date published: 2019-07-18
Rated 1 out of 5 by from This product is bad It is allll foam.. i was wondering why my son wasn't drinking it. There was nothing coming out of his bottle so i decided to chek and even if i squeeze the nipple nothing comes out its all foam.
Date published: 2019-06-24
Rated 5 out of 5 by from Best thing I found I can not believe my pediatrician did not know about this product to recommend. We tried so many other formulas before this one and the same constant spit up happened. My baby was healthy but kept spiting up Brest milk all the formulas we tried. And we were all just tired of doing laundry three times a day. Untill my husband happened to come across this Similac for spit up at a Walmart and decided to grab it. Thank you so much for this product it has saved us so much grief and my baby is actually feeding regularly now instead of every 10 minutes.
Date published: 2019-06-20
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