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Similac® For Spit-Up NON‑GMO*,†

For less frequent spit-up in healthy infants

Trust Similac For Spit-Up to give your baby the nutrition she needs.

Clinically shown to reduce frequent spit-up by 54%.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants and children with galactosemia.
Among healthy 2-month-old infants, compared to standard milk-based formula. Lasekan JB et al. J Am Coll Nutr. 2014;33:136-146.

NON-GMO Similac baby formula for reducing spit-up.

Available In:

1.41-lb Powder

32oz Ready to Feed

For spit-up in healthy infants

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac® For Spit-Up
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Similac For Spit-Up NON‑GMO Reviews

Rated 5 out of 5 by from Great product! We had so many feeding issues at first with my 3 month old son. My milk never came in so he was losing weight so I needed to supplement fast but he was also having gas issues so we tried similac sensitive but he would projectile vomit after every feed. He was diagnosed with acid reflux and put on similac for spit up, and it was like magic!!!! I had my happy baby again, we've had zero issues since starting this formula. He still will spit up here and there but nowhere near as bad or frequent as before. We did have to go up in nipple size because its thicker, I've found the Avent for colic bottles work best with this formula. Also I've heard constipation can be a issue but he has no problem with that he still poops every day. Thank you Similac!!!!
Date published: 2018-09-13
Rated 4 out of 5 by from This product is hard to find After trying diff kinds of formula this one way the only one that my baby could still gain weight. Other similacs didnt work. She kept spitting up alot and losing weight. Ive never had a problem with the bottles. She doesnt have trouble going to the bathroom. I also add cereal to her bottles. Only problem its hard to find. I have to go a half hr put of my way to find it.calling Similac is no help. She cant just have any type of formula if it causes a weight problem. Since shes been on this shes right on track. I have a hard time finding it. How can similac not help when I pay for this product. I shouldnt have to go to a few stores to get a couple cans while dragging a newborn around.
Date published: 2018-09-05
Rated 3 out of 5 by from No more spit up but constipated My son has reflux and was switched from pro advanced to the spit up formula. He no longer projectile vomits but he struggles so much to have a bowel movement. He also always has this congested sounding breathing after eating which didn’t happen on pro advanced. This formula definitely controls spit up I hate that it’s causing other issues and also the price is killing me!
Date published: 2018-08-09
Rated 1 out of 5 by from Horrible ! Decided to give this formula a go when my son started having scary projectile spit ups and every feeding spit up.. if anything this formula made it worse !! Larger volume of the spit up as well as clogging the bottles we used becuse the formula is so thick... after much experimenting we finally discovered similac sensitive works and is happy with it however I wasted $30 buying a container of this...
Date published: 2018-08-08
Rated 5 out of 5 by from Life Changer After trying so many different formulas we were recommend this one by UVA medical center. The baby was almost 2 months old and still under 7 lbs. In less then 2 weeks he is now over 8 lbs and still going. This formula has saved us from long drawn out hospital visits and tests as well as the worry that we were doing something wrong. Its pricey but what formula isnt. Wish I could give it 10 stars
Date published: 2018-08-06
Rated 4 out of 5 by from Works for spit up to a large degree however it creates a new issue, constipation Works for spit up to a large degree however it creates a new issue, constipation. Also this formula is extremely hard to find to purchase in stores plus 8 Oz ready to feed is non existent. The 8 ounce ready to feed bottles are needed!!! Enfamil provides the 8 ounce ready to feed for their version of this formula but I really want to stick with similac.
Date published: 2018-06-21
Rated 4 out of 5 by from Happier baby! He defintely does not throw up or spit up as much it has cut down BY FAR. Also this has been the only formula to keep him satisfied. He no longer cries after feeding or want to eat every hour. He seems to have constipation? I can’t tell. It has only been a day almost so we shall see. I hope it is just because he has to adjust to it. He was throwing up so much on similar pro advanced, advanced AND gerber soothe. He was the worst on gerber soothe.
Date published: 2018-06-03
Rated 5 out of 5 by from Game changer! We tried several different formulas before trying this one. I couldn’t be more pleased. Spitting up is now very minimal, my baby doesn’t scream in pain any longer. Y’all have to try. We also add dark karo syrup to bottle at night to help combat constipation.
Date published: 2018-05-22
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Has your family been affected by Hurricane Florence?

If you or someone you know has been affected, find out how Similac® can help.