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Similac® For Spit-Up NON‑GMO*,†

For less frequent spit-up in healthy infants

Trust Similac For Spit-Up to give your baby the nutrition she needs.

Clinically shown to reduce frequent spit-up by 54%.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants and children with galactosemia.
Among healthy 2-month-old infants, compared to standard milk-based formula. Lasekan JB et al. J Am Coll Nutr. 2014;33:136-146.

NON-GMO Similac baby formula for reducing spit-up.

Available In:

1.41-lb Powder

NoPalmOil-Video-2 No Palm Oil/Palm Olein Oil

For spit-up in healthy infants

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac® For Spit-Up
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Similac For Spit-Up NON‑GMO Reviews

Rated 4 out of 5 by from So far so good So far so good my baby been on spit up for a week now and since last Monday she has stop spitting up it’s some here and there but not as much as she was doing with Similac pro advance and she had a day senses she left the hospital three months ago. If she do spit up it’s not a whole lot. She spit up a whole lot tonight for the first time 7/9/2020 why idk but I will have a talk with her doctor in a few days to see if I should change it again. But overall I would recommend this milk
Date published: 2020-07-09
Rated 5 out of 5 by from I love it! We started off with Pro-Advance, then switched to Advanced from WIC. With Pro-Advance, baby didn't have any spit-up, neither did he have it with mother's milk. Once he turned 1 month and we switched to Advanced, he started to spit up a lot! He had a hard time keeping it down, and he wore 3 sets of clothes a day, and we did his laundry twice in 3 days because he kept spitting up on his clothes, his swaddles, and his 3 blankies. We saw Similac For Spit-up and was thinking about getting it. When I came home from work, I fed him and changed him, and he spat up twice afterwards. I ended up going to the local Kroger's because it was closer and got a jar. First feeding was 2 ounces, and he didn't spit up. I accidentally work him up, and his grandmother gave him another 2 ounces. He still didn't spit up, which was great! I have him another 2 ounces an hour and a half later and he has fallen asleep for almost 4 hours now! Still no spit up! Works wonders! I love it! He'll be getting hungry again soon, but it'll be mother's milk this time. Thank you, Similac!
Date published: 2020-05-25
Rated 5 out of 5 by from Amazing Our son was exclusively breast fed for 5 months. He has has spit up problems since birth - we were giving him medicine 3 times a day, we would run out of burp clothes daily, and we had to change his clothes and our clothes after each feeding because he would constantly spit up. He was still gaining weight well but it was so stressful and the laundry was a nightmare. With going back to work and having a hard time keeping supply up, we decided to switch him to formula and I’m so thankful we found this product. It was highly recommended by our pediatrician. At first we tried mixing it with breast milk and his stomach couldn’t handle it. The only time he wouldn’t throw up was if he was exclusively on this product. We have slowly started trying again with foods and he is thriving - his stomach just had to get used to the switch.
Date published: 2020-05-03
Rated 5 out of 5 by from Worked great! Of course with any product it takes time to work, but after a little while my son no longer throws up after he eats, and if he does it’s the tiniest bit just on his chin. I LOVE similar spit up. Does exactly what it says.
Date published: 2020-04-01
Rated 1 out of 5 by from Worst Product EVER, DOES NOT DO AS IT SAYS Wish I could give zero stars. Spit-up nor any other similac products have helped my son. Just making it worse along with other things. This formula has entirely to much sugar which leads to my son not wanting to try any other that probably him.
Date published: 2020-02-19
Rated 5 out of 5 by from Highly recommend Similac for Spit Up!! We have 10 week old twins, who’ve had issues with 4 other kinds of formula!! Started them off with Similac Advance, and it didn’t sit well with either of them. Their doctor said try Enfamil Nurtamigen ... that was the WORST formula, by far!! Not just the smell was bad, but it tore their tummies up!!! From there, we were told try Similac Alimentum, it was better than the Nurtamigen, but they were still having issues with diarrhea and spitting up. We decided we don’t need to visit the doctor, to try a new formula, so we went with the Similac Soy. It was okay, but the diarrhea was still there. Now we are solely on Similac for Spit Up, and it is amazing!!! Our girls haven’t been more content, and neither have had diarrhea or spit up. Like many have stated, the formula is thicker, so using the Dr. Brown’s nipple size 2 has been our best solution!! If we try to make the bottle by hand, it’s a little foamy, but if you plan ahead, it all settles. For our regular bottle making, we use the Baby Brezza ... our bottles always come out perfect, and there isn’t an issue with foam!!!
Date published: 2020-01-09
Rated 5 out of 5 by from This formula is a blessing! From birth my baby started on Similac Pro-Advanced and she was constantly spitting it up. She was switched to Similac for Spit-up while we were still in the hospital. After a few feedings she had stopped spitting up. I'm extremely thankful for this formula! Thank you!!
Date published: 2019-11-20
Rated 5 out of 5 by from Love it My son was on advance similac & he kept crying for 3 days & spitting up and hardly drinking his whole 4oz took him to his dr today & she switched his formula. Wow my son is drinking his whole bottle now(4oz) . Not every 5/10 min like he was doing those three last days with the advance !!! & he’s so calm now sleeping peacefully. It also isn’t foam. Mines doesn’t even have that
Date published: 2019-10-11
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