Similac® For Spit-Up NON‑GMO*,†

For less frequent spit-up in healthy infants

Trust Similac For Spit-Up to give your baby the nutrition she needs.

Clinically shown to reduce frequent spit-up by 54%.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants and children with galactosemia.
Among healthy 2-month-old infants, compared to standard milk-based formula. Lasekan JB et al. J Am Coll Nutr. 2014;33:136-146.

NON-GMO Similac baby formula for reducing spit-up.

Available In:

NON-GMO Similac baby formula for reducing spit-up. 1.41-lb Powder

Similac for Spit-Up 32oz formula for infants 1-qt Ready to Feed

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac® For Spit-Up
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Rated 4 out of 5 by from Does the job! Helps with spit up, but it clumps in the nipple.
Date published: 2017-01-18
Rated 4 out of 5 by from Helps w spit up for sure This has helped our son, but is VERY difficult to mix. Very clumpy & clogs the nipple.
Date published: 2016-12-23
Rated 4 out of 5 by from Doing much better Started with Similac Advanced for my 2 month old as breast feeding wasn't an option any more. He spit up so much and was cranky after every feeding. We switched to Similac for Spit Up and the amount of spit up has greatly reduced and he is much less cranky after feeding. The only issue we are having with this formula is that it does not always mix well. We often have large clumps of formula floating in the bottle sometimes obstructing the nipple. I do recommend this product.
Date published: 2016-12-17
Rated 5 out of 5 by from New mommy and happy baby FINALLY! We started on similac advance because that's what the hospital started him on. I never produced milk so I had to start bottle feeding. We stayed on similac advance and then tried the sensitive and I knew right away that wasn't going to work. It never filled him up and he was constipated. We switched back to advance but I just had a feeling it wasn't working for him. He then started spitting up a ton of formula. Almost 1oz right after feeding and he would scream in pain! I then checked reviews on here and decided to try the total comfort. That worked for a while but after a few weeks he started to get bad diarrhea and he was screaming in pain again. He would wake up from naps about every 30 min to an hour screaming in pain. I then decided to try the spit-up after my sister said it worked for her twin boys. I was really reluctant to switch formulas...again!! I'm so glad I did though! After the first bottle it was like a whole new baby! He was full and his belly didn't hurt. I actually called the doctors office for my baby being "too calm" and was worried. Now it did clog him up for a couple days. Totally normal with the thicker formula and the added rice in there, but after 2 days he finally had a blow out and he is back to perfect! I'm sooooo happy I switched and I finally feel like I have found the perfect thing for my baby boy! Also helped with my babies acid reflux! No more raspy voice from his stomach acid.
Date published: 2016-12-16
Rated 5 out of 5 by from Content baby Similac Spit-up is great. My daughter didn't do so well on Similac Advance. She's only seven-weeks-old, but she was always fussy and would cry like she was in pain. Immediately after switching to Similac Spit-up, she changed. It was like she was a different baby. She's content now. She doesn't ever cry unless she's hungry. So we exchanged all of the Advance formula for Spit-up. She's only been on Spit-up for two weeks, and I'm so thankful we changed her formula. I only wish a sample of this was given in the welcome box. It might have been in the hospital bag, but our hospital promotes breastfeeding, and therefore, does not offer the bags.
Date published: 2016-12-07
Rated 1 out of 5 by from Has, at the very least, doubled the spit-up! My fiance bought this formula with great enthusiasm that it would help our 13 week old daughter, but it's actually made her worse. She spits up most of her 4oz bottle (not exaggerating) soon after her feed almost every single bottle I've given here in the last 4 days. The results were like this the first day but i wanted to give it a chance. Switching back to the Similac Sensitive today.
Date published: 2016-11-29
Rated 5 out of 5 by from Best product on the market My son is 6 months old and at birth was spitting up A LOT. We went through Enfamil products when my doctor suggested Similac Spit Up, gave me a sample can and the rest is history!
Date published: 2016-11-27
Rated 1 out of 5 by from Doesn't do what it says Switched to this formula from similac supplement when I stopped breast feeding and she went from all smiles and happy to having painful gas and being very fussy along with still spitting up.
Date published: 2016-11-26
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