Similac® For Spit-Up NON‑GMO*,†

For less frequent spit-up in healthy infants

Trust Similac For Spit-Up to give your baby the nutrition she needs.

Clinically shown to reduce frequent spit-up by 54%.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants and children with galactosemia.
Among healthy 2-month-old infants, compared to standard milk-based formula. Lasekan JB et al. J Am Coll Nutr. 2014;33:136-146.

NON-GMO Similac baby formula for reducing spit-up.

Available In:

NON-GMO Similac baby formula for reducing spit-up. 1.41-lb Powder

Similac for Spit-Up 32oz formula for infants 1-qt Ready to Feed

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac® For Spit-Up
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Rated 3 out of 5 by Helps with spit ups At 16 days old this formula has been much better as far as spitting up goes, but it does seem to make pooping harder for him. October 17, 2016
Rated 5 out of 5 by Works wonders My son is five months old. I've tried so many formula's. Enfamils gentlease and he still was spitting up. I tried similac sensitive and it didn't do much justice. The Dr prescribed similac spit up and he's been doing well ever since ! I just wish there we're on the go bottles for this particular formula. I travel a lot and it would be very helpful. October 13, 2016
Rated 3 out of 5 by Still looking We breastfed for 9 weeks, then had to use formula. We tried Similac Advance but our son had bad spit ups. We went to sensitive and he did ok but still spit up quite a bit. Finally we tried this, and it works wonders. He doesn't spit up, but after a few weeks he is so severely constipated we had to manually disempact him (I'm a nurse fortunately) and he whimpers and cries in pain every time he pushes and tries to use the bathroom. We finally decided to switch when he would be so hungry but take a sip or two of this forumla then scream in pain. I had a sample can of the total comfort so I made a bottle and dumped the spit up out. As soon as he took a sip he calmed down and drank the whole bottle and was back to smiling. Hopefully this works for us. This product does work but I'm not sure if we are the only ones who had such awful side effects. October 12, 2016
Rated 5 out of 5 by So happy for my baby My baby boy is currently 9 weeks and for the first 9 weeks of his life he has been spitting up like crazy. I tried several different formulas (the ones that I was most familiar with). I started him on enfamil gentlese in the hospital and he was a little spit up baby but as we got home it began to get worse. I next went to gerber goodstart gentle and that gave the same results. Just recently I was speaking to a friend of mine and said that her baby does great with Similac advance (btw I breast feed. Mostly at night and in the morning b/c baby goes to daycare). I went to purchase similac and notice the kind for spit up. To make a long story short, my baby is sleeping more, seems more comfortable and is not spitting up!!!! October 4, 2016
Rated 5 out of 5 by Stops spit up My son was spitting up after every meal for 4 days straight. His pediatrician recommended trying this since the Similac Advanced wasn't working for him anymore. We received some samples and he has been doing great ever since! My only complaint is there needs to be "on the go" bottles and the pre-portion packs. We live an hour away from Austin and we travel there a lot... having these options would make traveling much easier! September 30, 2016
Rated 5 out of 5 by Has helped my daughter!! Helped my daughter from spitting up over 90% of the time!!!! Recommended over enfamil! Amayzing results! September 28, 2016
Rated 5 out of 5 by SPIT UP STOPPED IMMEDIATELY my daughter was all the sudden spitting up excessively with her Similac Advanced. This product is unbelievable. She completely stopped spitting up! September 26, 2016
Rated 5 out of 5 by What a difference this formula makes! When I stopped breast feeding, I was very concerned that my daughter would be at such a disadvantage. My doctor recommended Similac Advance telling me "it was the next best thing". I was committed to the brand but the advance did not sit well with my daughter and the spit up was out of control at every feeding. We thought it could be gas so we tried the Similac Sensitive but the spit up was still too much. She was spitting up all over our carpet, floors, couches, you name it. We have just switched to Similac Spit Up and in two days have seen a significant difference. She still spits up a little but not after every bottle and definitely a lot less. I hope it only gets better from here. September 25, 2016
  • 2016-10-24 T09:26:55.071-05:00
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