Similac® For Spit-Up NON‑GMO*,†

For less frequent spit-up in healthy infants

Trust Similac For Spit-Up to give your baby the nutrition she needs.

Clinically shown to reduce frequent spit-up by 54%.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants and children with galactosemia.
Among healthy 2-month-old infants, compared to standard milk-based formula. Lasekan JB et al. J Am Coll Nutr. 2014;33:136-146.

NON-GMO Similac baby formula for reducing spit-up.

Available In:

1.41-lb Powder

For spit-up in healthy infants

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac® For Spit-Up
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Similac For Spit-Up NON‑GMO Reviews

Rated 4 out of 5 by from Mixing This formula has significant reduced my sons spitting up. But it's so foamy even after the recommended 2 minutes of sitting. Am I doing it wrong?
Date published: 2019-03-30
Rated 4 out of 5 by from I love this but Working great for my daughter but I wish I could find bigger cans seems like it’s the only one they don’t make the bigger size in
Date published: 2019-03-27
Rated 1 out of 5 by from Made my baby’s spit up worse I’m sure this works for a lot of babies, and for them I’m really happy, but this is not working out for my baby. I switched her 48 hours ago and the sped up has gotten even worse. She didn’t sleep at all last night and she won’t stop crying. Not only that, but it clumps in the bottle and won’t dissolve. So glad I wasted $28 on formula to not be able to use it.
Date published: 2019-03-25
Rated 5 out of 5 by from Love this product My daughter has acid reflex and this formula has been great! It has reduced how much she spits up to practically nothing and she absolutely loves it. The only down side is that’s it’s hard to find. I’ve never tried the ready to feed, it’s not sold anywhere near me so I buy the powder. I have a formula mixer so it makes it very smooth. However I do wish they had ready to feed bottles! We had an incident with daycare over feeding her on a day my mom picked her up so she ended up having to find a store and buy a new box. Also stores near by have promotions going on sometimes except on this particular kind. Overall love the product just wish their was bottles for on the go or to keep as an emergency.
Date published: 2019-03-23
Rated 4 out of 5 by from Great Absolutely love it but have had to buy a formula mixer due to clumps... wish the ready to feed was still available
Date published: 2019-03-14
Rated 5 out of 5 by from Powder vs ready to feed. Ready to feed prefered. My LO is 6mo. and drinks both the powder and the ready to feed. They say theres no difference but I feel the ready to feed is a lot smoother for her to drink. The powder you have to mix well and even when it foams and you let it sit, its not as good as the ready to feed. I buy the powder because its hard to find the ready to feed. The ready to feed is worth buying if it helps my LO. Or is there a trick to mixing the powder hmm?...
Date published: 2019-03-11
Rated 3 out of 5 by from Formula I've tried a lot of formulas, but so far this one I have seen reduce my baby's spit up problem! I'm happy about that! The only few things I absolutely hate about this formula. Is the mixing! This formula does NOT mix well. If you put the water in first then the powder, the powder just sits on top of the water and doesn't dissolve until you shack it hard. And then sometimes the clumps stick inside the nipple or other parts of the bottle. Frustrating really! The other thing is, I really hate that this formula doesn't have the HMO like the others you have! Why is that? Since I couldn't breastfeed long, that eased my mind to know the formula had that like breastmilk. But this one does not and its disappointing that to cure one thing, you have to sacrifice another...
Date published: 2019-03-08
Rated 1 out of 5 by from So upset this isn’t available My baby is 3 months old and at about 10 weeks was diagnosed with acid reflux. We have went through about 5 different formulas in these 3 mos and NOTHING has worked for her. I finally tried the ready to feed for spit up and it’s been a life saver she’s been doing perfect and she loves it... now I find out that similac isn’t making the ready to feed anymore so I tried the powder and she hates it she is back to throwing up almost her entire bottle! I went to every store in town and bought the last of their ready to feed! I am so upset! Please bring it back!!!!!!!!!!!
Date published: 2019-02-26
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