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Similac® For Spit-Up NON‑GMO*,†

For less frequent spit-up in healthy infants

Trust Similac For Spit-Up to give your baby the nutrition she needs.

Clinically shown to reduce frequent spit-up by 54%.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants and children with galactosemia.
Among healthy 2-month-old infants, compared to standard milk-based formula. Lasekan JB et al. J Am Coll Nutr. 2014;33:136-146.

NON-GMO Similac baby formula for reducing spit-up.

Available In:

1.41-lb Powder

NoPalmOil-Video-2 No Palm Oil/Palm Olein Oil

For spit-up in healthy infants

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac® For Spit-Up
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Similac For Spit-Up NON‑GMO Reviews

Rated 5 out of 5 by from Worked great! Of course with any product it takes time to work, but after a little while my son no longer throws up after he eats, and if he does it’s the tiniest bit just on his chin. I LOVE similar spit up. Does exactly what it says.
Date published: 2020-04-01
Rated 1 out of 5 by from Worst Product EVER, DOES NOT DO AS IT SAYS Wish I could give zero stars. Spit-up nor any other similac products have helped my son. Just making it worse along with other things. This formula has entirely to much sugar which leads to my son not wanting to try any other that probably him.
Date published: 2020-02-19
Rated 5 out of 5 by from Highly recommend Similac for Spit Up!! We have 10 week old twins, who’ve had issues with 4 other kinds of formula!! Started them off with Similac Advance, and it didn’t sit well with either of them. Their doctor said try Enfamil Nurtamigen ... that was the WORST formula, by far!! Not just the smell was bad, but it tore their tummies up!!! From there, we were told try Similac Alimentum, it was better than the Nurtamigen, but they were still having issues with diarrhea and spitting up. We decided we don’t need to visit the doctor, to try a new formula, so we went with the Similac Soy. It was okay, but the diarrhea was still there. Now we are solely on Similac for Spit Up, and it is amazing!!! Our girls haven’t been more content, and neither have had diarrhea or spit up. Like many have stated, the formula is thicker, so using the Dr. Brown’s nipple size 2 has been our best solution!! If we try to make the bottle by hand, it’s a little foamy, but if you plan ahead, it all settles. For our regular bottle making, we use the Baby Brezza ... our bottles always come out perfect, and there isn’t an issue with foam!!!
Date published: 2020-01-09
Rated 5 out of 5 by from This formula is a blessing! From birth my baby started on Similac Pro-Advanced and she was constantly spitting it up. She was switched to Similac for Spit-up while we were still in the hospital. After a few feedings she had stopped spitting up. I'm extremely thankful for this formula! Thank you!!
Date published: 2019-11-20
Rated 5 out of 5 by from Love it My son was on advance similac & he kept crying for 3 days & spitting up and hardly drinking his whole 4oz took him to his dr today & she switched his formula. Wow my son is drinking his whole bottle now(4oz) . Not every 5/10 min like he was doing those three last days with the advance !!! & he’s so calm now sleeping peacefully. It also isn’t foam. Mines doesn’t even have that
Date published: 2019-10-11
Rated 3 out of 5 by from On the fence about this product I'm not sure how I feel about this formula.My little one is still spitting up and now seems like he is constipated.we have gone from ok m neosure to sensitive to alimentum and now this only plus is the smell is ten times better then the alimentum.I just hope we soon find the right formula for my little one that helps with is reflux and doesn't cause other issues.I also dont like that I cant find ready to feed or on the go in this formula.
Date published: 2019-10-01
Rated 5 out of 5 by from Excellent product My baby is 4 months now and we been using this products for 2 months .. she wasn’t able to hold nothing on her tummy and we tried this product and it was like magic.. it was such a change ..
Date published: 2019-08-25
Rated 2 out of 5 by from Made Spit Up Worse We have went from Pro Advance to Sensitive to Nutramigen back to Sensitive to Similac for Spit Up. Spit up started getting worse after Similac for Spit Up and my son seemed grumpy. I’d rather deal with spit up then have a grumpy baby. Going back to Sensitive and dealing with it
Date published: 2019-08-24
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