Similac® For Spit-Up NON‑GMO*,†

For less frequent spit-up in healthy infants

Trust Similac For Spit-Up to give your baby the nutrition she needs.

Clinically shown to reduce frequent spit-up by 54%.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants and children with galactosemia.
Among healthy 2-month-old infants, compared to standard milk-based formula. Lasekan JB et al. J Am Coll Nutr. 2014;33:136-146.

NON-GMO Similac baby formula for reducing spit-up.

Available In:

NON-GMO Similac baby formula for reducing spit-up. 1.41-lb Powder

Similac for Spit-Up 32oz formula for infants 1-qt Ready to Feed

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac® For Spit-Up
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Rated 5 out of 5 by from It works! After having difficulty breastfeeding my newborn I started supplementing. We started with Similac pro advantage. Almost immediately my newborn began spitting up a lot. She was spitting up 6-7 times immediately after eating and again an hour or so later. She was spitting up way more than a tablespoon. Her bib would be soaked along with her clothes and us. When I was shopping I came upon this product in the clearance rack. Thinking it wouldn't hurt to give it a shot. So glad I did. We had immediate results. She still spits up some but it's now a normal amount. I highly recommend this product. Only downside I have found is that it's thicker than normal formula. It clogs at times in a size 1 nipple but comes out too fast in size 2. So I constantly battle between the two sizes to try to see which one appeases my baby at the moment. Other than that it's great.
Date published: 2017-05-21
Rated 3 out of 5 by from This product is good I do like the fact of the milk thickness but the problem is that the milk is blocking the nipple of the bottle though my baby is 4 months and I am using level 3 nipples !! so he's getting tired and not completing his meal then becoming very fussy to deal with !! Any recommendation???
Date published: 2017-05-20
Rated 5 out of 5 by from For Spit Up - works for us My five month old daughter was constantly spitting up and puking from feeding to feeding. We have been on many other formulas like sensitive, pro sensitive, and total comfort. We've been on this formula now for two weeks and the spitting up and puking is now at a minimal. I hope this is the answer to her problems! I also think because of the added rice starch in it has really helped. Thank you Similac!
Date published: 2017-05-19
Rated 2 out of 5 by from Made baby cry all day I switched to spit up bc my 3 month old was spitting up so much but unfortunately it didn't help at all in fact it made it worse. Prior to this I was using Similac Pro sensitive even though she was spitting up it suited her better. I use Similac spit up for 3 days and then gave up and went back 2 using Pro sensitive.
Date published: 2017-05-15
Rated 5 out of 5 by from Life Saver My little girl was born 1/19/2017. I was hospitalized 2/12/2017 for over a week due to a ruptured appendix. Infection was draining into my body for days before I checked into the ER. I was breastfeeding. Due to the surgery, the heavy antibiotics and narcotics my supply took a major hit and is now completely gone. We had to immediately switch her to formula. Her pediatrician recommended Similac Advance (new silver can) but she was not keeping this down. Then we were told to try Enfamil AR. This was so much worse. The whole bottle was coming right back up. Then we tried Similac Spit up. This is PERFECT. She keeps it down and babygirl is happy. What a life saver!!!! We love Similac. Happy baby means happy mom. Happy mom means happy family. :) Thank you. We trust our littlest with Similac.
Date published: 2017-05-07
Rated 5 out of 5 by from Love it! I love this product and so does my little man! I'm using it and breast feeding about every 2-3 feedings. I only produced from one side and I only get about 2 ounces every feeding. He seems to be content with eating
Date published: 2017-04-13
Rated 2 out of 5 by from Ok product This product didn't help my baby..he is 3 weeks old and he had a small spit up problem so my husband and I decided to give it a actually made his spit up worst and he wasn't getting full. He usually eats 4 oz and is full but I fed him 4 oz and he was still hungry so we went back to our old faithful formula.. I do like the fact that this product is thicker and he didn't have milk running everywhere after we fed him but didn't work and he wasn't full after feedings
Date published: 2017-04-10
Rated 3 out of 5 by from Less spit up but not completely gone ): Since our daughter was born she has been having issues with spitting up a lot. We started off with Enfamil enfacare for premies at the hospital. Once home we continued and she kept spitting up then later turned into full blow projectile vomiting. So we tried the enfamil gentlease and it was still happening. After every feeding even after keeping her up right all the time. Then we tried similar advanced. Then Similac sensitive. She remained the same. Now we are on similac for spit up. We slowly transitioned her into it. The spit up seems to happen still but it's much less. Now it seems like she might be having trouble passing stool. Ita only been two days since she has pooped. So I'm still hoping she will be fine. Don't know what else to do! All my other babies did fantastic with Similac. Hoping I can find something for this one.
Date published: 2017-03-31
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