Similac® For Spit-Up NON‑GMO*,†

For less frequent spit-up in healthy infants

Trust Similac For Spit-Up to give your baby the nutrition she needs.

Clinically shown to reduce frequent spit-up by 54%.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants and children with galactosemia.
Among healthy 2-month-old infants, compared to standard milk-based formula. Lasekan JB et al. J Am Coll Nutr. 2014;33:136-146.

NON-GMO Similac baby formula for reducing spit-up.

Available In:

NON-GMO Similac baby formula for reducing spit-up. 1.41-lb Powder

Similac for Spit-Up 32oz formula for infants 1-qt Ready to Feed

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac® For Spit-Up
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Rated 5 out of 5 by from Wonderful! At about a month old my daughter started having acid reflux and spitting up all the time. Since I switched to this formula she has not had any problems! Worked wonders!
Date published: 2017-10-17
Rated 5 out of 5 by from This formula works for my preemie baby My twin boys were born at 32 weeks. One of them had really bad reflux which caused him to stop breathing. The doctors tried multiple formulas and this one finally worked. The ready to feed formula is hard to find in stores, wish it was more readily available.
Date published: 2017-10-17
Rated 5 out of 5 by from Good for our Baby Help him to reduce his refluxe
Date published: 2017-10-11
Rated 4 out of 5 by from Great until it wasn’t This product helped or daughter stop spitting up but now she’s extremely constipated and just developed a rash. We are assuming she had an allergic reaction to it or may have a milk allergy. I’m extremely frustrated :( I’m not sure what formula to use now.
Date published: 2017-09-21
Rated 4 out of 5 by from helpful product, but more sizes should be available. This product has significantly reduced my son's spit up. The one major issue we have is the powder clumps and causes blockages in the nipples which irritates my son and in turn us. Due to that I have started buying the ready to feed quart bottles. I like the ready to feed option, but the quart size bottles are not convenient for on the go. An 8 oz ready to feed option should become available.
Date published: 2017-09-09
Rated 2 out of 5 by from Not that great! I need HELP! My baby has a spit up problem and I've been struggling with all the milks I don't know which milk to try. She was on similac advance but she would throw it all up. Then sensitive but still keeps throwing it up now spit up but still doesn't work and I don't know what to do now!!! Help!!!
Date published: 2017-09-06
Rated 4 out of 5 by from Clogging Nipple We used this formula with my first baby and it was wonder. It did exactly what I wanted it to do. When we had our second baby and we're have the same spit up issues I turned to this formula. Unfortunately, I have been having such a hard time getting it to flow out of the bottle, it keeps clogging the nipple. We used Dr Brown bottles both times so I am not sure why this time we are having such a hard time. We spend more time fighting the bottle and formula than I do feeding. It's really annoying. Any suggestions?
Date published: 2017-08-28
Rated 5 out of 5 by from Worked well for us. At eleven days old our daughter was diagnosed with acid reflux. Her pediatrician recommended we switch to this formula. We're about a week into using it and so far it has worked wonders for our baby. I have no complaints and in thankful this exists. We went from projectile vomiting to none at all.. Love this product! BFox
Date published: 2017-08-26
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