Similac® For Spit-Up NON‑GMO*,†

For less frequent spit-up in healthy infants

Trust Similac For Spit-Up to give your baby the nutrition she needs.

Clinically shown to reduce frequent spit-up by 54%.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants and children with galactosemia.
Among healthy 2-month-old infants, compared to standard milk-based formula. Lasekan JB et al. J Am Coll Nutr. 2014;33:136-146.

NON-GMO Similac baby formula for reducing spit-up.

Available In:

1.41-lb Powder

1-qt Ready to Feed

For spit-up in healthy infants

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac® For Spit-Up
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Similac For Spit-Up NON‑GMO Reviews

Rated 4 out of 5 by from Works for spit up to a large degree however it creates a new issue, constipation Works for spit up to a large degree however it creates a new issue, constipation. Also this formula is extremely hard to find to purchase in stores plus 8 Oz ready to feed is non existent. The 8 ounce ready to feed bottles are needed!!! Enfamil provides the 8 ounce ready to feed for their version of this formula but I really want to stick with similac.
Date published: 2018-06-21
Rated 4 out of 5 by from Happier baby! He defintely does not throw up or spit up as much it has cut down BY FAR. Also this has been the only formula to keep him satisfied. He no longer cries after feeding or want to eat every hour. He seems to have constipation? I can’t tell. It has only been a day almost so we shall see. I hope it is just because he has to adjust to it. He was throwing up so much on similar pro advanced, advanced AND gerber soothe. He was the worst on gerber soothe.
Date published: 2018-06-03
Rated 5 out of 5 by from Game changer! We tried several different formulas before trying this one. I couldn’t be more pleased. Spitting up is now very minimal, my baby doesn’t scream in pain any longer. Y’all have to try. We also add dark karo syrup to bottle at night to help combat constipation.
Date published: 2018-05-22
Rated 4 out of 5 by from Works but hard to find Baby #4 is our first baby to not handle Similac Sensitive she was still spitting up so much that she dropped weight in percentile so our pediatrician recommended switching to Similac Spit Up we had been looking for it in case that was going to be the answer but our local stores (in a major city) carry very low stock (1 store had 1 another store had 2). So with that being the case we asked if we could try a different brand for spit up that was a bad idea it made the spit up worse so we quickly got the Similac Spit Up and within A day saw a difference. Yes even size 2 nipples get clogged but we pinch the clog through and she’s back to drinking with no problems. She still spits up but now it’s not liquid soaking everything and she’s clearly keeping more in. Just wish more options were available like the 8oz ready to feed for travel and that it was easier to find
Date published: 2018-05-07
Rated 3 out of 5 by from Thick formula that you need a bigger nipple size I had high hopes for this product and was let down. The label should tell you that it will not flow through a size one nipple. My little one was sucking away(trying to eat) for hours. The little food he did eat, he managed to spit it up. It had a chunky consistency, unlike the spit up from the pro advanced formula. I tried to thin the formula out with water, and that seemed to cause my little one stomach pains. I wonder what size nipple works with this formula. Also, if it’s normal for my little one’s spit up with this formula to be chunky. Hopefully customer service will be able to answer my questions.
Date published: 2018-04-10
Rated 5 out of 5 by from great product the product has helped my baby from throwing up and spitting up so often. now she only spits up just a little to none at all. very satisfied with this formula and will be recommending it to other mothers.
Date published: 2018-03-16
Rated 5 out of 5 by from This formula really helped my son. My newborn son’s pediatrician recommended Similac for Spit Up because of his constant spitting up. It has dramatically helped him to not spit up as much. We had the same problem with the nipple clogging. But we just switched from the #1 nipple to the #2 nipple and we have had no more problems with nipples clogging.
Date published: 2018-03-10
Rated 4 out of 5 by from This product helped This product helped my daughter with her feedings and her constant spitting up. But like many others, this formula clogs the nipples. Is this formula thicker?? What’s recommended to use with this formula?
Date published: 2018-02-01
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