Similac® Soy Isomil®

Complete nutrition for sensitive tummies

Fussiness and gas can be a common part of feeding your baby.

Similac Soy Isomil is specially designed to comfort with the gentleness of soy to soothe the tummy.

Soy-based formulas have been clinically shown to help reduce feeding problems. No other soy-based formula has been studied more than Isomil.

Has OptiGRO to support your baby's brain and eye development.

If your baby’s fussiness or gas seems excessive, ask your physician about switching to Similac Soy Isomil.

Soy formulas are not recommended for premature infants with birth weights of less than 1800 g.

Similac Soy Isomil formula product for infants

Available In:

1.45-lb Powder

12.4-oz Powder

1-qt Ready to Feed

Soy for fussiness and gas

Nutrition Information

Powder / 1.45 lb

Serving size: 100 Cal (prepared as directed)*

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

* Nutrient values are applicable when prepared as directed.

Similac® Soy Isomil®
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Similac Soy Isomil Reviews

Rated 5 out of 5 by from Great Product My daughter has been on this since 3 Months old she was having tummy issues so we tried it and it was like magic in a bottle! But she is now 10 Months and I am looking for a toddler transition formula that’s milk and lactose free can anyone help me with that? Or do I just keep feeding this formula?
Date published: 2018-12-07
Rated 4 out of 5 by from Made all the difference in the world My baby was born premature weighting just over 3lbs at birth. He never mastered the latch and I never produced enough milk for him so formula became or best friend. We tried several brands and types of formula, including other similac products but has the same result with all of them, Gassiness, fussing like he was in pain, constipation, loads of spit up, and show weight gain even though he was in a high calorie diet. After 2 months I finally asked my pediatrician about isomil because it was the only formula I could handle a a baby according to my mom. The doctor said normally they don't recommend it with preemies but since he was having issues let's try it. Within 2 days I noticed a difference, no fussiness, very little spit up and gas, and no more constipation. Also he started gaining weight. Where most babies double they're birth weight by 6 months old he has more than quadrupled his, now weighing over 14lbs. I have no doubt in my mind that if we didn't switch to isomil he would still be struggling to gain weight. My only complaint is that it's so expensive, we go through the 1.45lb the of isomil every 4 days and even through I've signed up for coupons I've only received them once and it's been over six months and even then the coupons were for neosure so I couldn't use them. Over all through it's a great product.
Date published: 2018-12-03
Rated 5 out of 5 by from Only formula that worked We had a very fussy, gassy, bearing down baby after trying Similac pro advance, pro sensitive, and enfamil gentle ease. All of these caused her great discomfort. We tried gripe water, gas drops etc. Similac Soy Isomil was the ONLY thing that worked!! No more fussy! When she was newborn- 2 months she did get constipated so we did add a little Gerber apple juice to her bottles which helped. But this formula is a life saver and my 6 month old is now a happy, right on track baby!
Date published: 2018-11-25
Rated 5 out of 5 by from Really helped my son’s sensitive tummy My LO had really bad stomach cramps, very gassy, and could not tolerate the similac Alimentum. After switching to the soy Isomil we no longer have any issues. Thanks to the soy formula my LO can finally be comfortable and rest peacefully
Date published: 2018-11-21
Rated 2 out of 5 by from Clumpy We used Similac Hypoallergenic with my first and had great success. Similac sent us a free sample and coupons during this pregnancy so we were happy to use it again. Recently had to switch to this soy formula tho and I am not thrilled. It is very hard to get it to dissolve completely when mixing. At first it wasn’t an issue because I make a days worth in a pitcher and the clumps don’t pour into the bottles. However, I always buy 8oz ready-to-feed bottles for the diaper bag to avoid clumps when I’m out and about, but I can’t find them in the soy anywhere! Will likely switch to Enfamil, who sells the 8oz bottles everywhere.
Date published: 2018-11-08
Rated 1 out of 5 by from My girl was screaming her head off I gave her only a few feeds before she was on parents choice and did fine I don't know what happened she started screaming in pain. I really was looking forward to using Similac too because it worked for my first born. I am disappointed that it didn't work for the money I paid.
Date published: 2018-11-04
Rated 5 out of 5 by from Wonderful transition! I LOVE this formula my daughter is almost 4 months and has been using this since she was 1 month with assistance of breast feeding. I’ve been a vegetarian for 9 1/2 years so she’s never experienced “regular milk”(cow milk). The hospital insisted on me giving her regular milk and I couldn’t figure out why she kept throwing up(through nose and mouth) and her fussiness. Long story short we seen a nutritionist and they suggested this formula. She’s been great every since!
Date published: 2018-10-30
Rated 5 out of 5 by from The difference was night and day! We ended up in the ER with my two week old for bloody stools and they determined it may be from a dairy intolerance so we switched to the Similac Soy and it has made a night and day difference. No more bloody stools and she hardly ever fusses from gas anymore. I finally can get some rest so this has been a lifesaver!
Date published: 2018-09-17
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