Similac® Soy Isomil®

Complete nutrition for sensitive tummies

Fussiness and gas can be a common part of feeding your baby.

Similac Soy Isomil is specially designed to comfort with the gentleness of soy to soothe the tummy.

Soy-based formulas have been clinically shown to help reduce feeding problems. No other soy-based formula has been studied more than Isomil.

Has OptiGRO to support your baby's brain and eye development.

If your baby’s fussiness or gas seems excessive, ask your physician about switching to Similac Soy Isomil.

Soy formulas are not recommended for premature infants with birth weights of less than 1800 g.

Similac Soy Isomil formula product for infants

Available In:

1.45-lb Powder

12.4-oz Powder

1-qt Ready to Feed

Soy for fussiness and gas

Nutrition Information

Powder / 1.45 lb

Serving size: 100 Cal (prepared as directed)*

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

* Nutrient values are applicable when prepared as directed.

Similac® Soy Isomil®
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Similac Soy Isomil Reviews

Rated 3 out of 5 by from Helped with my son's gas but... My son always had difficult time with gas so his pediatrician suggested we switch him from enfamil gentlease to Similac Soy, at first it worked great he was passing gas burping with no issues. But then he began to become constipated, when he did poop as he was passing it he was struggling and cried. As a mother it broke my heart to see him so much in pain. Plus when you mix the formula it has so much foam and bubbles, not good to feed. Waiting for then to settle is not an option when u have a screaming hungry baby at 2 am in the morning.
Date published: 2018-06-25
Rated 4 out of 5 by from This product has been so helpful My guy couldn’t tolerate anything else so this is the product we have been using for the past 5 months. Before this he was always throwing up, gassy, and constipated but he’s now 8 months old and started out a 4lb preemie and is now a 19lb 8 month old. I still receive Neosure coupons for the Strong Moms rewards but I can’t use them.
Date published: 2018-05-24
Rated 1 out of 5 by from this formula didn’t settle well with my son my 3 week old ended up with bloody stool, so his pediatrician said he had a milk allergy. his doctor changed his formula to Enfamil Prosobee which ended up settling great with his tummy and saw a changed in his stool the same day. for financial reasons the pediatrician had to change formula from Enfamil to Similac Isomil, thinking it would work exactly the same because both formulas are soy based, and i was very wrong. this formula led my son to have even more watery stool than with the original milk based formula. i was very disappointed i have to return to the doctor to get my sons formula changed once again.
Date published: 2018-04-15
Rated 2 out of 5 by from This product casued my son constipation all the time. We have been through almost all the formula Similac has to offer soy was our last option. My son did the worst by far on the soy it caused him severe constipation and discomfort and he would still be spitting up a lot 2 hours after he ate . He was also on the pro advance and he spit up a lot on that so we switched him to the pro sensitive and he spit up a lot and it was always chunky. We also tried the spit up and it was to thick for him to get out of his bottle. We switched back to the pro advance because he seems to do the best on it.
Date published: 2018-03-30
Rated 3 out of 5 by from Hoping This Eventually Works We are now on our FOURTH formula in our daughters short three months! We started with Enfamil Newborn from the hospital, that ended up giving her horrible gas pains nonstop. We switched to Enfamil Gentlease, it got better then worse again. So we switched to Smililac Pro-Sensitive it again got better then WAY worse and she was having diarrhea that turned to constipation. We are now using the Similac Soy. It is starting to possibly make a difference but she still has pretty bad gas pains. We say a GI doctor and she put her on a laxative but I really don't want to have to use it. She said soy is very binding. She no longer has diarrhea but her gas pains are still there. Hoping the soy will continue to make a difference or we will unfortunately, once again, will be on the hunt for a new formula. :(
Date published: 2018-03-20
Rated 5 out of 5 by from This product has helped my baby. My 3 month old has been suffering from eczema. She has had dry patches of skin all over her little body. The blotches were getting worse and we couldn't figure out what was going on. We switched creams, bath products and detergent. So we figured it had to be internal. On a bunch, I switched her to the Similac Soy hoping she had a milk allergy and bingo! It's only been a few days and her skin is clearing up wonderfully. The poor thing would tear her skin up itching it all night and finally she has some relief. Thank you Similiac.
Date published: 2018-03-12
Rated 5 out of 5 by from Solved all my problems! My poor baby girl was so fussy with all formula after we switched her from breast milk (couldn’t make enough). Poor little girl would scream for hours with the worst gas. Started the soy formula at 2 weeks & we saw a change in her within the first 24hrs! Thank you!
Date published: 2018-02-07
Rated 5 out of 5 by from LIFESAVER! My baby was breast fed only until she was about 2 and a half months old...had trouble with milk flow so I had to start supplementing, started with PRO-sensitive but she started screaming 24/7! She was not herself, crying so hard and stiffing her body so bad and not sleeping, switched to this soy, now she is such a happy baby and sleeps ALL NIGHT!!!!!! Thank you Similac!!!!!! You have saved us with this formula!!!!
Date published: 2018-01-26
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