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Similac® Soy Isomil®

Complete nutrition for sensitive tummies

Fussiness and gas can be a common part of feeding your baby.

Similac Soy Isomil is specially designed to comfort with the gentleness of soy to soothe the tummy.

Soy-based formulas have been clinically shown to help reduce feeding problems. No other soy-based formula has been studied more than Isomil.

Has OptiGRO to support your baby's brain and eye development.

If your baby’s fussiness or gas seems excessive, ask your physician about switching to Similac Soy Isomil.

Soy formulas are not recommended for premature infants with birth weights of less than 1800 g.

Similac Soy Isomil formula product for infants

Available In:

1.45-lb Powder

12.4-oz Powder

1-qt Ready to Feed

Soy for fussiness and gas

Nutrition Information

Powder / 1.45 lb

Serving size: 100 Cal (prepared as directed)*

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

* Nutrient values are applicable when prepared as directed.

Similac® Soy Isomil®
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Similac Soy Isomil Reviews

Rated 5 out of 5 by from The difference was night and day! We ended up in the ER with my two week old for bloody stools and they determined it may be from a dairy intolerance so we switched to the Similac Soy and it has made a night and day difference. No more bloody stools and she hardly ever fusses from gas anymore. I finally can get some rest so this has been a lifesaver!
Date published: 2018-09-17
Rated 5 out of 5 by from This formula helped my baby My baby had really bad tummy problems until we tried this formula. He started gaining weight and was less cranky after each feeding. Helped control gas too.
Date published: 2018-09-07
Rated 5 out of 5 by from Amazing!!! Our little girl gets so gassy and fussy, even with breastmilk. We tried a lot of formulas but this one is gold!!! She loves it, whereas she would spit the others out. It has been a life saver and she barely has any gas or fussiness on this product. We love it, and it's all she will drink.
Date published: 2018-09-05
Rated 5 out of 5 by from This is great if your little one has a sensitive tummy Our little girl started on reg similac at the hospital, once we got home we noticed her tummy was being bothered so we changed her to soy, it has been like gold to us! And the coupons weget have helped so much!!!
Date published: 2018-08-13
Rated 5 out of 5 by from Has to be the ready made My son cried for about 20 hours a day for 2 months before we found that the soy isomil ready made was all he can tolerate. He cannot have the powder as the corn syrup content is too high and upsets his stomach. I find this very hard to find and I have to drive an hour to get some if I don’t order for delivery from Walmart on time or if the shipment comes late. However, this is the only thing that helped and I am SO grateful for that.
Date published: 2018-08-04
Rated 1 out of 5 by from Not a pleasant experience We wanted a milk free formula for our baby who is 1 month old & we used similac soy which caused her sever constipation & gas. I’m sad that it didn’t work for her since we didn’t want to give her milk but enfamil infant & breast milk are best for her.
Date published: 2018-08-01
Rated 5 out of 5 by from Better than the competitors At our 1 month check up, the pediatrician suggested we switch to Soy. Our son had been so gassy and fussy he was uncomfortable all the time. We left the appointment with a competitor's sample and instructions to immediately switch to it. The doctor knew we had been using a milk based Similac formula, and offered that if we saw positive results from the soy based formula samples, we could switch the Similac soy. We saw an improvement within hours, and switched the Similac Soy Isomil. We prefer the Similac because while the soy based products are hard to dissolve in water, the Similac powder doesn't clump the way the competitors did, which makes it easier to dissolve. We wish it came in a larger container, but for now we will just have to buy it by the case.
Date published: 2018-07-23
Rated 3 out of 5 by from Helped with my son's gas but... My son always had difficult time with gas so his pediatrician suggested we switch him from enfamil gentlease to Similac Soy, at first it worked great he was passing gas burping with no issues. But then he began to become constipated, when he did poop as he was passing it he was struggling and cried. As a mother it broke my heart to see him so much in pain. Plus when you mix the formula it has so much foam and bubbles, not good to feed. Waiting for then to settle is not an option when u have a screaming hungry baby at 2 am in the morning.
Date published: 2018-06-25
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Has your family been affected by Hurricane Florence?

If you or someone you know has been affected, find out how Similac® can help.