Similac® Soy Isomil®

Complete nutrition for sensitive tummies

Fussiness and gas can be a common part of feeding your baby.

Similac Soy Isomil is specially designed to comfort with the gentleness of soy to soothe the tummy.

Soy-based formulas have been clinically shown to help reduce feeding problems. No other soy-based formula has been studied more than Isomil.

Has OptiGRO to support your baby's brain and eye development.

If your baby’s fussiness or gas seems excessive, ask your physician about switching to Similac Soy Isomil.

Soy formulas are not recommended for premature infants with birth weights of less than 1800 g.

Similac Soy Isomil formula product for infants

Available In:

1.45-lb Powder

12.4-oz Powder

1-qt Ready to Feed

Soy for fussiness and gas

Nutrition Information

Powder / 1.45 lb

Serving size: 100 Cal (prepared as directed)*

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

* Nutrient values are applicable when prepared as directed.

Similac® Soy Isomil®
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Similac Soy Isomil Reviews

Rated 3 out of 5 by from Limited options My baby was supplementing with Similac, then Similac Sensitive and now Similac Isomil to curb some of the vomiting. I prefer to use ready to feed as it is more efficient. Since I am supplementing, I don't need to use a whole bottle in 48 hours as the directions prompt. Tossing it is a waste of money. Please consider making this in the 8 oz ready to feed bottles for the convenience of tossing expensive milk. I also live in a large metro city and have a hard time finding the ready to feed.
Date published: 2019-12-01
Rated 5 out of 5 by from Worked for my son My son is 5 weeks old. We notice that he was super fussy, gassy (smelt like rotten eggs), stool was very watery, and he slept horrible. I did some research on why his farts smelt so bad. Basically it all came back has he was lactose sensitive. Before switch we had the free ones you get. Similac Pro-advance and sensitive and both still made him not feel good. So we switch to similac soy and it was magic in a bottle. I also BF. He gets about 15 oz a day from me. So far similac soy is working for us. He finally pooped. I was worried because i read it can made babies constipated but my boy was right on schedule and it was thick and green. Yay for soy.
Date published: 2019-10-22
Rated 5 out of 5 by from similac SOY I would like to be able to receive coupons for this particular soy formula. Works GREAT!!! POOR help with any coupons:(
Date published: 2019-10-01
Rated 4 out of 5 by from Sensitive tummy My baby has a very sensitive tummy and we've tried a bunch of different formulas and Similac Soy seems to be working well for him. My only complaint isn't with the formula but with the rewards program, I never receive any checks in the mail and the online codes don't work. Even though the soy formula is more expensive, if it makes my baby feel better it's worth it!
Date published: 2019-08-28
Rated 4 out of 5 by from Solved tummy troubles, but caused constipation! My 4 month old has been having tummy troubles since birth. Gentle formulas, Sensitive formulas and the allergy formula all didnt help the extreme gas and discomfort. Well, my mother suggested we try soy because I was a soy formula baby in the 90s amd wow! What a difference! Shes been on it about 7 weeks now and no longer has the gas pain or tummy aches. However, this does make her constipated and she has such a hard time pooping that we've had to start giving an ounce of prune juice daily under doctors orders. She still strains to poop and only has little hard poops, not mushy or liquidy like they used to be. Not sure if i should be adding a probiotic or not, but I'll take her crying for 20 minutes trying to poop VS 6 hours of screaming because of gas!
Date published: 2019-08-09
Rated 4 out of 5 by from Works great for my baby We tried regular Similac formula and Gentlease Similac, but my daughter got very sick with both. Lots of throwing up and upset stomach for the 24-48 after drinking it. Our pediatrician gave us a sample of this Soy formula, and it has worked great! No fussiness or issues with it. Very grateful for another option.
Date published: 2019-07-19
Rated 5 out of 5 by from This is great for my daughter. I love the soy formula however i wish you had coupons for it.
Date published: 2019-06-29
Rated 4 out of 5 by from Good alternative for newborns needs My son was diagnosed with Duarte Galactosemia after his newborn screen. I was exclusively breastfeeding him but our pediatrician recommended we supplement with a soy based formula until we have our follow up with a geneticist. So far he seems to be ok switching over. He is not pooping as much and seems to have some gas but nothing severe. The only issue we have is the’s so expensive and we don’t qualify for any assistance. Of course we will continue on the soy until we get the all clear from the doctor, even with the extra expense.
Date published: 2019-06-12
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