Similac® Soy Isomil®

Complete nutrition for sensitive tummies

Fussiness and gas can be a common part of feeding your baby.

Similac Soy Isomil is specially designed to comfort with the gentleness of soy to soothe the tummy.

Soy-based formulas have been clinically shown to help reduce feeding problems. No other soy-based formula has been studied more than Isomil.

Has OptiGRO to support your baby's brain and eye development.

If your baby’s fussiness or gas seems excessive, ask your physician about switching to Similac Soy Isomil.

Soy formulas are not recommended for premature infants with birth weights of less than 1800 g.

Similac Soy Isomil formula product for infants

Available In:

1.45-lb Powder

12.4-oz Powder

1-qt Ready to Feed

Soy for fussiness and gas

Nutrition Information

Powder / 1.45 lb

Serving size: 100 Cal (prepared as directed)*

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

* Nutrient values are applicable when prepared as directed.

Similac® Soy Isomil®
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Similac Soy Isomil Reviews

Rated 4 out of 5 by from Sensitive tummy My baby has a very sensitive tummy and we've tried a bunch of different formulas and Similac Soy seems to be working well for him. My only complaint isn't with the formula but with the rewards program, I never receive any checks in the mail and the online codes don't work. Even though the soy formula is more expensive, if it makes my baby feel better it's worth it!
Date published: 2019-08-28
Rated 4 out of 5 by from Solved tummy troubles, but caused constipation! My 4 month old has been having tummy troubles since birth. Gentle formulas, Sensitive formulas and the allergy formula all didnt help the extreme gas and discomfort. Well, my mother suggested we try soy because I was a soy formula baby in the 90s amd wow! What a difference! Shes been on it about 7 weeks now and no longer has the gas pain or tummy aches. However, this does make her constipated and she has such a hard time pooping that we've had to start giving an ounce of prune juice daily under doctors orders. She still strains to poop and only has little hard poops, not mushy or liquidy like they used to be. Not sure if i should be adding a probiotic or not, but I'll take her crying for 20 minutes trying to poop VS 6 hours of screaming because of gas!
Date published: 2019-08-09
Rated 4 out of 5 by from Works great for my baby We tried regular Similac formula and Gentlease Similac, but my daughter got very sick with both. Lots of throwing up and upset stomach for the 24-48 after drinking it. Our pediatrician gave us a sample of this Soy formula, and it has worked great! No fussiness or issues with it. Very grateful for another option.
Date published: 2019-07-19
Rated 5 out of 5 by from This is great for my daughter. I love the soy formula however i wish you had coupons for it.
Date published: 2019-06-29
Rated 4 out of 5 by from Good alternative for newborns needs My son was diagnosed with Duarte Galactosemia after his newborn screen. I was exclusively breastfeeding him but our pediatrician recommended we supplement with a soy based formula until we have our follow up with a geneticist. So far he seems to be ok switching over. He is not pooping as much and seems to have some gas but nothing severe. The only issue we have is the’s so expensive and we don’t qualify for any assistance. Of course we will continue on the soy until we get the all clear from the doctor, even with the extra expense.
Date published: 2019-06-12
Rated 4 out of 5 by from Awesome My son started out on breast milk however I wasn't producing enough so we decided to put him on formula. The hospital used Enfamil but when we got home all versions of it was not working. So my friend suggested the Similac due to the spit up and I tried the spit version and it worked great he had less spit up. However it came back stronger and my baby sitter said we should try a lactose free formula and I did and he has loved it ever since. The only issue is the cost of the formula it is so expensive. My 3 month old runs through 1.45lb in four to five days.
Date published: 2019-05-15
Rated 5 out of 5 by from Excellent formula for combo feeding with dairy intolerance We started supplementing breastfeeding at 7 month because of a dip in supply. We tried ProAdvance and ProSensitive, but my little couldn’t tolerate either. We suspected a dairy intolerance, (we later found that she has a casein sensitivity) and switched to Similac Soy Isomil. Her fussiness and digestive issues cleared right up. We also tried Enfamil Soy, but we had much better results with Similac. She off of formula now, and we were able to easily transition her to soy milk.
Date published: 2019-03-29
Rated 5 out of 5 by from So gentle My daughter was put on pro-advance at the hospital when I wasn’t producing enough milk. Then the pediatrician put her on total comfort at 3 weeks old. Now at 8 months she was still having terrible reflux and stomach discomfort. I did some research and felt soy was worth giving a try. It’s been about a week on Isomil and I can tell she’s having less reflux and it seems so gentle on her belly.
Date published: 2019-01-21
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