Similac® Soy Isomil®

Complete nutrition for sensitive tummies

Fussiness and gas can be a common part of feeding your baby.

Similac Soy Isomil is specially designed to comfort with the gentleness of soy to soothe the tummy.

Soy-based formulas have been clinically shown to help reduce feeding problems. No other soy-based formula has been studied more than Isomil.

Has OptiGRO to support your baby's brain and eye development.

If your baby’s fussiness or gas seems excessive, ask your physician about switching to Similac Soy Isomil.

Soy formulas are not recommended for premature infants with birth weights of less than 1800 g.

Similac Soy Isomil formula product for infants

Available In:

1.45-lb Powder

12.4-oz Powder

1-qt Ready to Feed

Soy for fussiness and gas

Nutrition Information

Powder / 1.45 lb

Serving size: 100 Cal (prepared as directed)*

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

* Nutrient values are applicable when prepared as directed.

Similac® Soy Isomil®
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Similac Soy Isomil Reviews

Rated 4 out of 5 by from Awesome My son started out on breast milk however I wasn't producing enough so we decided to put him on formula. The hospital used Enfamil but when we got home all versions of it was not working. So my friend suggested the Similac due to the spit up and I tried the spit version and it worked great he had less spit up. However it came back stronger and my baby sitter said we should try a lactose free formula and I did and he has loved it ever since. The only issue is the cost of the formula it is so expensive. My 3 month old runs through 1.45lb in four to five days.
Date published: 2019-05-15
Rated 5 out of 5 by from Excellent formula for combo feeding with dairy intolerance We started supplementing breastfeeding at 7 month because of a dip in supply. We tried ProAdvance and ProSensitive, but my little couldn’t tolerate either. We suspected a dairy intolerance, (we later found that she has a casein sensitivity) and switched to Similac Soy Isomil. Her fussiness and digestive issues cleared right up. We also tried Enfamil Soy, but we had much better results with Similac. She off of formula now, and we were able to easily transition her to soy milk.
Date published: 2019-03-29
Rated 5 out of 5 by from So gentle My daughter was put on pro-advance at the hospital when I wasn’t producing enough milk. Then the pediatrician put her on total comfort at 3 weeks old. Now at 8 months she was still having terrible reflux and stomach discomfort. I did some research and felt soy was worth giving a try. It’s been about a week on Isomil and I can tell she’s having less reflux and it seems so gentle on her belly.
Date published: 2019-01-21
Rated 5 out of 5 by from Works great!!! I just purchased the milk today and gave my daughter two bottles so far. When i say it works wonders it works wonders!!! She was on breast milk then when she wasnt gaining weight off my milk i supplemented with the pro advantage. The pro advanted had her constipated and she was always hungry,fussy and gassy. I switched to the pro sensitive she was no longer constipated but she still stayed hungry and was more fussy and gassy to where i couldnt sleep n the pacifier wasnt working. Today i decided to put her on soy n she has been full after her feeding she wasnt crying like she normally do she was quiet looking around and smiling. When it was time for her to go to sleep she went to sleep with no problems. She wasnt crying and didnt even need her pacifier. She sooooo calm i keep checking to make sure she okay lol. I love this milk so far!!!!!!
Date published: 2019-01-19
Rated 5 out of 5 by from This product worked well with all 3 of my children With all three of my children, Similac Soy has been our formula of choice and has settled the best in their stomachs. I highly recommend this product, especially if your infant experiences gassiness.
Date published: 2019-01-15
Rated 5 out of 5 by from Amazing Best thing to happen to our household! I have a new baby with the help of this formula
Date published: 2019-01-03
Rated 5 out of 5 by from Great Product My daughter has been on this since 3 Months old she was having tummy issues so we tried it and it was like magic in a bottle! But she is now 10 Months and I am looking for a toddler transition formula that’s milk and lactose free can anyone help me with that? Or do I just keep feeding this formula?
Date published: 2018-12-07
Rated 4 out of 5 by from Made all the difference in the world My baby was born premature weighting just over 3lbs at birth. He never mastered the latch and I never produced enough milk for him so formula became or best friend. We tried several brands and types of formula, including other similac products but has the same result with all of them, Gassiness, fussing like he was in pain, constipation, loads of spit up, and show weight gain even though he was in a high calorie diet. After 2 months I finally asked my pediatrician about isomil because it was the only formula I could handle a a baby according to my mom. The doctor said normally they don't recommend it with preemies but since he was having issues let's try it. Within 2 days I noticed a difference, no fussiness, very little spit up and gas, and no more constipation. Also he started gaining weight. Where most babies double they're birth weight by 6 months old he has more than quadrupled his, now weighing over 14lbs. I have no doubt in my mind that if we didn't switch to isomil he would still be struggling to gain weight. My only complaint is that it's so expensive, we go through the 1.45lb the of isomil every 4 days and even through I've signed up for coupons I've only received them once and it's been over six months and even then the coupons were for neosure so I couldn't use them. Over all through it's a great product.
Date published: 2018-12-03
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