Similac® Soy Isomil®

Complete nutrition for sensitive tummies

Comfort your baby's fussiness and gas with Similac Soy Isomil — specially designed with the gentleness of soy to soothe the tummy.

Some issues, such as fussiness and gas, are a common part of feeding your baby. However, if these common feeding issues continue, ask your physician about switching to Similac Soy Isomil.

Soy-based formulas such as Similac Soy Isomil have been clinically shown to help reduce these feeding problems. And no other soy-based formula has been studied more than Isomil®.

Soy formulas are not recommended for premature infants with birth weights of less than 1800 g.
Similac® Soy Isomil®
tummy care guarantee
Parents know that every tiny tummy is unique.

So if your baby's tummy doesn't agree with a Similac product,
you can try another one FREE*

*Refund of purchase price (excluding taxes and shipping) on select products
only. Limit 2 refunds per household. Must redeem within 30 days of purchasing
alternative formula.

Similac now has OptiGRO

OptiGRO is our unique blend of DHA, Lutein and Vitamin E; these important ingredients are found in breast milk.

  • DHA for brain and eye development

  • Lutein to support eye health

  • Vitamin E an important nutrient found in breast milk to support developing cells

OptiGRO is available in most Similac formulas.

Knowing Means Growing™

Formula types

  • Powder formula
  •  |  Ready To Feed formula
Powder formula
Ready To Feed formula

Powder formula

Just add powder formula to water and mix.
Similac® Soy Isomil® SimplePac

Available in the Similac® SimplePac®

Mom Preferred. Similac SimplePac. And chosen easier to use 3 to 1 over the Enfamil® refill tub.*

*Formula Package Study 2010.

Feeding solutions

It takes time for a baby’s digestive system to mature, so a fussy baby
doesn’t have to mean switching formulas. 

Always talk to your pediatrician about feeding issues before making a switch.
Soy formulas are not recommended for premature infants with birth weights of less than 1800 g.

Before switching, try these suggestions:

  • Use a different bottle or nipple.
  • Use a different burping position.
  • Adjust your body position.
  • Use liquid formula instead of powder.

Have more feeding questions?

Go to Feeding Expert 
Keep learning about your baby's development every week
Get nutrition guidance and feeding help delivered right to your inbox.  
Join Similac® StrongMoms® now.   

Your Similac StrongMoms membership is free, and includes:
  • Expert nutrition guidance for your pregnancy
  • Weekly updates on how your baby is developing and growing
  • Up to $329 in membership benefits
Offers may vary.  
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Rated 4.9 out of 5 by 80 reviewers.
Rated 5 out of 5 by Best formula ever! We have been struggling trying to find a formula my daughter can tolerate. We have tried more types and brands than I can count. FINALLY, we found the Similac Isomil Concentrate. Until now, every morning we had to clean severe dirty, diarrhea diapers and/or she would be covered in spit up. It had gotten so bad we had to let her sleep with us as we were scared to let her sleep without one of us close by. All because she couldn't tolerate any formula we tried or regular milk. After just one night of using this formula, we woke up to a clean, dry and happy baby! She has gone through an entire can and not one time has she spit up. This stuff is a God send! October 6, 2015
Rated 5 out of 5 Love it for fussy baby Great for gas fussiness and allergies September 4, 2015
Rated 5 out of 5 by Great product!!! This product has always been great!! We used it for our first baby cause she had milk allergy and now we are using the same similac soy for our second baby. Both babies have gained the right amount of weight. Never had a problem using this product. September 3, 2015
Rated 5 out of 5 by ⭐️⭐️⭐️⭐️⭐️ Tried several formulas for supplementing. Have had great results with Soy, zero spitting up and seems to be digested easily. We use the ready made, not the powder. I wish the 2oz size was more easily available, sometimes we don't use the full 8oz and I hate wasting it. Baby gets about 4oz of this a day. September 1, 2015
Rated 5 out of 5 by When I couldn't use regular formula for my acid reflux baby, I was so glad you guys made this!!!!! When I couldn't use regular formula for my acid reflux baby, I was so glad you guys made this!!!!! She responded very well to it and loves it!!! So thankful for Isomil!! August 31, 2015
Rated 5 out of 5 by Lactose problem solved Our son developed a lactose allergy at about 5 months. We switched to the soy and have had zero problems. August 30, 2015
Rated 5 out of 5 by This is the best formulaout there. My daughter had a lot of spit ups, and regular formula just wasn't sitting well with her. We choose Similac Soy because our first daughter was put on it also. We trust this brand, and know that its the BEST there is!!! August 30, 2015
Rated 5 out of 5 by The only thing my son did not get sick from My son started on regular similac advance and unfortunately it made him so gassy and he was not having regular bowl movements. On a second chance we tried the similac sensitive which made his tummy even more upset bc now he wasnt going for 5 to 6 days and was spitting up after every feeding. Scared and frustrated we heard that the similac soy formula worked well with babies who had sensitive tummys, now my son is going to the bathroom normally and is no where near as fussy as he has been. I would recommend this formula to those parents who are struggling to find the better formula for the sensitive tummies out there. August 30, 2015
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