Similac® Soy Isomil®

Complete nutrition for sensitive tummies

Fussiness and gas can be a common part of feeding your baby.

Similac Soy Isomil is specially designed to comfort with the gentleness of soy to soothe the tummy.

Soy-based formulas have been clinically shown to help reduce feeding problems. No other soy-based formula has been studied more than Isomil.

Has OptiGRO to support your baby's brain and eye development.

If your baby’s fussiness or gas seems excessive, ask your physician about switching to Similac Soy Isomil.

Soy formulas are not recommended for premature infants with birth weights of less than 1800 g.

Similac Soy Isomil formula product for infants

Available In:

Similac Soy Isomil 1.45lb formula for infants 1.45-lb Powder

Similac Soy Isomil 12.4oz formula for infants 12.4-oz Powder

Similac Soy Isomil 32oz formula for infants 1-qt Ready to Feed

Nutrition Information

Powder / 1.45 lb

Serving size: 100 Cal*

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

* Nutrient values are applicable when prepared as directed.

Similac® Soy Isomil®
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Rated 5 out of 5 by Wonderful!! This product has worked wonders for my daughter!! Galactosemia baby that can't have any milk or dairy, this product is literally a life saver. Her growth is off the charts, 96% for height and 93% for weight! Her specialist says she's the "picture of health" Thanks Similac! April 28, 2016
Rated 4 out of 5 by This is a good product but breast is excellent. I started breastfeeding from the beginning but ended up having to supplement. We tried Honest Co. organic, Similac organic and both left Baby with horrific constipation. Finally, we tried Soy Isomil in the ready-to-feed containers. Our only issue is the horrible smell of Baby's poo and gas. Her stool never had an odor until we put her on formula. However, we are grateful for the Similac Soy Isomil brand. Would you please consider providing organic soy formula soon? Thank you for the non-GMO samples we received this week. We won't use them because the Soy Isomil has been good for our baby's growth and development but we will certainly pass the samples on to a wonderful mom who will use them. April 27, 2016
Rated 2 out of 5 by Taste is good while testing some formulas to see which one is going to best for my baby girls tummy and this just made it worse, she was fussier and it seemed she was in pain trying to pass gas, when she did go it was thick and a dark green color (very dark), I probably should have gave it more then a week but after seeing her in pain i switch to similac organic April 18, 2016
Rated 5 out of 5 by Love Love this product. Is there anyway to get coupons??Used it with my first and started with my second child but can't afford it will have to switch to a cheaper formula. With my first child I was mailed coupon. April 4, 2016
Rated 3 out of 5 by Will this product cause constipation My baby have try this fomula for three weeks, some times he poo very two days and the poo are thick then before why? April 2, 2016
Rated 5 out of 5 by Lifesaver! We tried many different formulas for our daughter and nothing seemed to keep her happy and comfortable. For many weeks she was either asleep or fussing and crying. It was heartbreaking to listen to her cry all day. About a week ago we started Similac Soy. Immediately after her first bottle she was like a new baby. She seemed content and had smiles for everyone throughout the rest of the day. Here we are a week later and she is still doing great!. She only fusses when she's hungry or sleepy and spends the rest of the day peaceful and content. Similac Soy has been an absolute lifesaver for us!!! (I've seen several other posts about the Soy formula causing constipation our pediatrician recommended a probiotic supplement and we have not had any issues.) April 2, 2016
Rated 5 out of 5 by Round the clock care! Brought home our little prince from the hospital on Similac Advanced. Within a few days to a week he would continually spit up mouth fulls of his formula. No vomiting, or colic, and no diarrhea, and little constipation. The Dr, (not my normal doctor), did not really want to change his formula because he was growing so well. However, I knew this was not right. About 30 to 45 minutes after every feeding he would start spitting up mouth fulls of formula. This would continue until either he had spit up all that was left in his stomach; or until his stomach was empty enough to finally settle down. I tried burping him after every ounce, and feeding him less at a meal and more often with the same results. At the WIC office they suggested putting him on Similac Spit-Up formula. I said okay, as I had been dealing with this for nearly 3 months. It seemed to work at first, but then the spitting up started up within a couple of days. I contacted the WIC office and because he is gaining weight they claimed that he was just going to be a "Happy Spitter-Upper". Finally made a appointment with my longtime pediatrician, (this is my 9th child), as soon as I described what was happening he immediately switched him to Similac Soy Isomil. Within 24 hours of starting the Soy formula his spitting up stopped. He still has a sensitive stomach which we will watch closely, but at 8 months old he is 20 pounds 8 ounces and 30 inches long. April 1, 2016
Rated 2 out of 5 by Seemed to help at first... I would recommend this product to parents with a baby who has dairy issues and can handle soy. My baby was originally on Similac Neosure because she is a preemie, then she was put on Similac Spit up because of her really bad acid refllux. Then, she was put on Similac Sensitive for a number of weeks because the Similac Spitup was making her have diarrhea. But while she was on the Sensitive, she was also extremely gassy, and rarely slept at night due to gas pains and stomach discomfort. I made the switch to Similac Isomil which was recommended by her pediatrician since the thought was that she had an intolerance to dairy. It seemed to help the first 3 days. She actually took short naps at night, which she hadn't done in weeks and weeks. But, now she is right back to where she started, but worse. She is also constipated on top of all the original problems, and she is also not sleeping during the day. I am not getting any sleep either. We are both extremely exhausted. Not sure what to pick at this point. She hates the Enfamil formula, she really dislikes the taste of it. March 29, 2016
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