Similac Total Comfort

For discomfort due to persistent feeding issues

If your baby is experiencing discomfort due to persistent feeding issues, Similac Total Comfort may help.

Partially broken-down protein promotes easy digestion.

Has OptiGRO to support your baby's brain and eye development.

Similac Total Comfort powder formula for infants

Available In:

Similac Total Comfort powder formula for infants 1.41-lb Powder

Similac Total Comfort 12oz formula for infants 12.0-oz Powder

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac Total Comfort™
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Rated 5 out of 5 by Wonderful product I really love this formula. Our son was born in April 15. I hemorrhaged & wasn't making any milk. He was losing weight so the lacatation consultant gave him this to supplement through a tube at the breast. My milk never ended up coming in completely so we continued to nurse once a day & supplement with this. Then I started to switch him to the similac sensitive to get him on similac advance & he started having issues. His face broke out & he was having diarrhea & bad tummy pain & spitting up. I took him to the pediatrician & she told me to switch back to the total comfort. So I did & it's been wonderful! His skin cleared up for the most part. And his stools have been normal. & he stopped spitting up. This is a great formula! May 22, 2016
Rated 5 out of 5 by we tried multiple similac brands but this one is the best for us!! When I had our son I pumped for 2 weeks but he was losing weight quickly so I switched to similac. We tried the advanced and the sensitive but nothing was working, my son would scream out in pain after every bottle. I decided I'd give similac one more chance and get the Total Comfort. It was the best decision I could've made, my son immediately did better after the first bottle and ever since we've been using this type. It has been our life saver. No more gas pains or constipation. Thank you similac!!! May 19, 2016
Rated 3 out of 5 by Helped with gas but caused liquid stools My baby was having trouble with gas so we switched to this formula & it helped with the gas but now everytime I change his diaper its a black puddle!! We've switched back to the Non- GMO and he seems to be doing better. May 18, 2016
Rated 2 out of 5 by crazy experience when my daughter was first born she was breast fed. 5 wks after the nicu put her on similac neosure. when she came home she was constipated and fussy. i then tried allimentum but no use so finally, i did some research and found total comfort for discomfort. in the begining it worked perfect she slep through the night and went to the bathroom regular. this week she is now starting to spit up more and it seems she is always hungry. im making an appointment for the gi doc but i dont know what else to try. May 17, 2016
Rated 5 out of 5 by Finally a formula that works! After countless attempts of trying to find formulas for my son who was always constipated and fussy we thought we came to an end with no conclusion. Then I made one last try, and bought similac total comfort, and will never turn back!! Thank you so much :) May 15, 2016
Rated 5 out of 5 by tummy troubles over! I knew my little one was going to have to switch from breast milk to formula because he would be in daycare. When I first made the switch I started with enfamil and I noticed he was a little constipated and when he did have a bowl movement it was very watery. I then switched to gerber brand and this was a huge mistake. He stopped up for over 24 hours and screames bloody murder poor guy. I finally switched to similac total comfort and within 24 hours he pooped twice and has been regular ever since. It was a lifesaver and I haven't looked back. Thank you similac!! May 13, 2016
Rated 3 out of 5 by Caused horrible smell & constant eating I really liked this at first because the colic issues my baby was having were gone. (we also use Playtex VentAire) but then I noticed that he was constantly hungry, even 10 minutes later, nothing would stop his crying other than another bottle but my doctor said he needed to eat less. He eats it quick too so I'm sure he likes the taste but he also acts like he's starving. Then his bowel movements changed for the worse. They were a huge mess, watery, constant and smelled like something died causing gnats in our munchkin diaper pale and stinking up our house. I will have to change formulas. May 9, 2016
Rated 5 out of 5 by Lifesaver for twins My twin girls were born at nearly 36 weeks. They were unable to latch for breastfeeding, so we quickly turned to pumping and supplementing to get their weight up. We tried everything, but they had difficulties processing it and were always uncomfortable. We tried Total Comfort at the recommendation of our pediatrician, and haven't looked back! They are doing so much better now and gaining plenty of weight. May 8, 2016
  • 2016-05-23 T05:37:10.086-05:00
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