Similac Total Comfort NON‑GMO*,†

Complete nutrition for delicate tummies

If your baby is experiencing discomfort due to persistent feeding issues, Similac Total Comfort NON‑GMO may help.

Partially broken-down protein for easy digestion.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants or children with galactosemia.

Similac Total Comfort NON-GMO formula for easy digestion.

Available In:

Similac Total Comfort NON-GMO formula for easy digestion. 1.41-lb Powder

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac Total Comfort™ NON-GMO
Similac logo

New Moms

Join Similac® StrongMoms® Rewards for up to $400* in customized benefits, free gifts and exclusive savings.
Strongmom Decor Dsk
REGISTER *Offers may vary.
Rated 1 out of 5 by from Makes baby have even more gas We just switched to this from Similac Advance due to gas & spit up but after only 2 days my daughter has even more gas & seems fussier. And since this is only available in powder I don't know if she just doesn't agree with powder. Not sure if we should stick it out a few more days or if the extra gas is a sign to go back.
Date published: 2017-01-21
Rated 2 out of 5 by from Foamy and Gas producing I tried this with my 3wk old, it was very foamy and gave him terrible gas. We tried it for several days and he was very fussy. He was able to drink it easy but I think the foam was giving him extra gas.
Date published: 2017-01-20
Rated 1 out of 5 by from Not what I thought it would be I've changed my daughter formula multiple times. She has issues with gas and spit up. We were on Similac Advanced. Made her very gasy fussy and constipated. Then we switched to Enfamil Gentle. It didn't help the fussyness or gas. It also made her extremely constipated. Then we switched to Enfamil Reguline. It helped her constipation tremendously however we were still having the spit up. So now we're on Similac Total Comfort. Which seems to keep helping her with the constipation but the spit up is worse. It also doesn't seem to keep her full for very long. She's wanting to eat ever 2 hours instead of every 4 like normal. So now we're on the hunt for another formula. I just wish I could've breast fed because it doesn't seem like I'm ever going to find a formula that works for her.
Date published: 2017-01-20
Rated 3 out of 5 by from switching to similac senistive This formula makes my son way too gassy were switching to senisitive. I would not recommend this formula.
Date published: 2017-01-20
Rated 5 out of 5 by from Amazing product with satisfactory outcome I had a preemie of 34 weeks GA with low birth weight on 12/03/2016. On post discharge, she was put on breast feeding and a top up of Enfamil A+ for Premature & Low Birth Weight until 12/31/2016. Her physician switched to Similac, Isomil due to moderate diarrhoea and sepsis. On one week feeding, she developed a tummy discomfort such as reflux, gastric pain etc. On doctor advice, we switched formula to Similac, Sensetive and we have noticed no change. Finally, after 10 days baby crying due to abdominal pain and other associated issues, we started feeding our baby with Similac, Total Comfort and glad to see that her tummy problems resolved on second bottle. We are feeling now a big relief and a thums up to Similac Team for producing such a wonderful formula.
Date published: 2017-01-15
Rated 5 out of 5 by from Helped My preemie A Ton My baby boy was born 5 weeks early and he was given similac neosure in Nicu and that is what I was told to give him at home as well when we cam home a week later. Let me not forget I was breastfeeding as much as possible the neosure was to help make sure he was getting enough nourishment and gaining weight. Within the first two weeks of being home he was miserable arching his back crying and fussing trying to pass gas and was crazy spiting up. Our Family Docotor had us try total comfort and we have no more problems with gas any longer the arching and fussing went away. LO spitting up happens to be just his acid re flux, but love this formula!!!!!
Date published: 2017-01-15
Rated 5 out of 5 by from Constipation Free Baby! My baby bear was born Oct 1 2016. We started him on breast milk and he did fine with it but unfortunately I wasn't producing enough to feed often. We got him started on Similac advance and he had a fit! Very gassy and fussy, cried way to much. His doctor then changed him to Similac Sensitive given that he was actually a colic baby and that formula made no difference. We finally changed to Similac Organic and he did so well with that one but, it made him very constipated. His doctor didn't want to change him formulas again so my breast milk was actually a great laxative per say. We would give him organic and breast milk to help with his stools. Being that it was VERY expensive we decided on Total Comfort and it was great!. Drank his bottle entirely and almost immediately had a bowel movement. No fussiness, no tummy aches, passes gas and still does well with mommy's milk. I'm so glad he's no longer constipated. My only concern is that his stools are very dark sometimes black to dark green. Other than that very satisfied.
Date published: 2017-01-13
Rated 5 out of 5 by from So happy to have a happy baby! My oldest did fantastic with Similac Advance, so we started there with our youngest daughter. Advance left her very very gassy and fussy. Quickly after we switched to the Sensitive. She did a bit better on it and we just assumed that she was a more colicky baby. After several weeks and troubles with gas and a tight belly we decided to give this a shot. This was only two days ago and it has already made a huge difference! It has been heartwarming to have a happy, comfortable baby. I'm not sure if this is a coincidence, but last night was also our first time sleeping through the night! I wish we had tried this sooner instead of having the poor girl suffer through the gas pains, but now we know! It is a couple bucks more per canister, but it is worth it.
Date published: 2017-01-12
  • y_2017, m_1, d_23, h_3
  • bvseo_bulk, prod_bvrr, vn_bulk_0.0
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_202
  • loc_en_US, sid_sim-prod-410, prod, sort_[SortEntry(order=AGE, direction=DESCENDING), SortEntry(order=FEATURED, direction=DESCENDING)]
  • clientName_similac
  • bvseo_sdk, net_sdk,
  • CLOUD, getReviews, 31ms