Similac Total Comfort

For discomfort due to persistent feeding issues

If your baby is experiencing discomfort due to persistent feeding issues, Similac Total Comfort may help. It has partially broken-down protein for easy digestion. Plus, it has added Lutein and DHA to help your baby’s developing eyes and brain.

Similac Total Comfort™
tummy care guarantee
Parents know that every tiny tummy is unique.

So if your baby's tummy doesn't agree with a Similac product,
you can try another one FREE*

*Refund of purchase price (excluding taxes and shipping) on select products
only. Limit 2 refunds per household. Must redeem within 30 days of purchasing
alternative formula.

Similac now has OptiGRO

OptiGRO is our unique blend of DHA, Lutein and Vitamin E; these important ingredients are found in breast milk.

  • DHA for brain and eye development

  • Lutein to support eye health

  • Vitamin E an important nutrient found in breast milk to support developing cells

OptiGRO is available in most Similac formulas.

Knowing Means Growing™

Formula types

  • Powder formula
Powder formula

Powder formula

Just add powder formula to water and mix.
Similac Total Comfort™ SimplePac

Available in the Similac® SimplePac®

Mom Preferred. Similac SimplePac. And chosen easier to use 3 to 1 over the Enfamil® refill tub.*

*Formula Package Study 2010.

Feeding solutions

It takes time for a baby’s digestive system to mature, so a fussy baby
doesn’t have to mean switching formulas. 

Always talk to your pediatrician about feeding issues before making a switch.

Before switching, try these suggestions:

  • Use a different bottle or nipple.
  • Use a different burping position.
  • Adjust your body position.
  • Feed your baby less formula at each feeding while her digestive system grows.
  • Use liquid formula instead of powder.

Have more feeding questions?

Go to Feeding Expert 
Keep learning about your baby's development every week
Get nutrition guidance and feeding help delivered right to your inbox.  
Join Similac® StrongMoms® now.   

Your Similac StrongMoms membership is free, and includes:
  • Expert nutrition guidance for your pregnancy
  • Weekly updates on how your baby is developing and growing
  • Up to $329 in membership benefits
Offers may vary.  
Get up to $329† in great offers. Sign up now >

Rated 4.7 out of 5 by 47 reviewers.
Rated 4 out of 5 by This worked for us. We couldn't nurse and our baby developed reflux. this was the only type that didn't upset his tummy. i wish it came in larger tubs. November 11, 2015
Rated 5 out of 5 by Best for sensitive tummies Total Comfort was the third Similac formula we tried. When we did the transition from breastmilk to formula we were already supplementing with Similac Supplement and then tried Similac Advance alone. With the transition our son developed stomach problems having no bowel movements and extra fussiness and crying. When we went to the see his Pediatrician she recommended Similac Total Comfort. It was so much better for his stomach and we noticed a difference right away. Throughout the days the fussiness went away and his bowel movements were back to normal. I highly recommend this to parents who have little ones with sensitive stomachs as it's easier for them to digest. It made a world of a difference for us. It's a bit pricey but it's what works for us. November 7, 2015
Rated 4 out of 5 by great My baby was having gas issues thank God this one helped her out October 18, 2015
Rated 5 out of 5 by Finally..... We finally found the formula that works for my twin girls. They were born at 32 weeks, and were on Neosure added to breastmilk for several weeks. Unfortunately, at 14 weeks, I was no longer able to breastfeed my girls. We tried several formulas and the girls both were so fussy, gassy, and crying all the time. Finally, they have seemed to settle down with this formula. They only occasionally spit up or vomit. It has been great. I really wish we had Similac coupons though. Especially with us feeding two infants - on extra calorie as well. We have to use 3 scoops to every 150mL of water. We go through the larger container of Similac Total Comfort every day and a half. I receive coupons from the other companys, but have stopped receiving them from Similac for some reason. Any help with this would be greatly appreciated Similac !!! Thank you!!!! October 13, 2015
Rated 5 out of 5 by love this product my daughter was born at 35 weeks, with her being a preemie she had a hard time digesting foods, we tried the sensitive, and the soy, the total comfort was the only one that did not make her projectile vomit, nor was she fussy, she actually ate and entire bottle and was able to have solid stools. I recommend this product for any moms with babies that have a hard time digesting September 21, 2015
Rated 5 out of 5 by So thankful for this formula! We tried about 5 different kinds before we tried this one for my son. This is the only kind that didn't constipate him and make him have horrible gas problems. We still use gas drops at times, but it's not often. It's pretty sticky and hard to mix in his bottles though. I feel like there's always some clumps that won't mix. And I wish this came in the premixed bottle. (32 oz I think?) I have found every kind but total comfort in the premixed kind! September 20, 2015
Rated 5 out of 5 by Finally a formula that works for my baby! Similac Total Comfort was the sixth formula I tried for my very gassy, fussy newborn. He is now almost 4 months old and we've been using Total Comfort for about 6 weeks. We tried other formulas for sensitive tummies, both from Similac and other brands. We even tried a soy formula. He always seemed so uncomfortable due to his gas and tummy troubles. He's still fairly gassy, but he does so much better on Total Comfort. I just wish I could find more Similac coupons! The other brands are always sending me coupons in the mail. September 17, 2015
Rated 4 out of 5 by Best so far I started using this formula for my daughter a month ago and it works! She is no longer gassy or fussy and poops everyday. I tried so many formulas in her three months of life that I am so happy I don't have to look any further. However, she occasionally spits-up but it isn't as bad as it used to be prior to this formula. I would have given it 5 stars but there is NOT a pre-mixed liquid version for sale. I prefer to have a pre-mixed version for the sitter. PLEASE SIMILAC MAKE THIS FORMULA IN A PRE-MIX LIQUID VERSION ASAP!!! Thank you! September 11, 2015
  • 2015-11-27 T13:54:00.317-06:00
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