Similac Total Comfort NON‑GMO*,†

Complete nutrition for delicate tummies

If your baby is experiencing discomfort due to persistent feeding issues, Similac Total Comfort NON‑GMO may help.

Partially broken-down protein for easy digestion.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants or children with galactosemia.

Similac Total Comfort NON-GMO formula for easy digestion.

Available In:

Similac Total Comfort NON-GMO formula for easy digestion. 1.41-lb Powder

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac Total Comfort™ NON-GMO
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Rated 3 out of 5 by from Terrible gas pains My son was put on Similac soy at the hospital but became so constipated he was going a week at a time with no bowel movements. When he did have one he screamed in pain and strained. His doctor moved him to total comfort but now he has horrible gas pains and screams and cries until he throws up most of his bottle. His doctor tried moving him back to the soy formula but he projectile vomits on that. So she moved him back to total comfort because he is still gaining so it seemed he does not need the hypoallergenic formula. I guess we take crying and a slightly lesser amount of spit up/vomiting over constipation and exorcism vomiting. It is a shame because my oldest was a similac baby just wish we could find one that works for our youngest but we keep having to buy cans of formula and then throw most of it out. Oh and as you mix the powder if you mix it even a little to vigorously it becomes foam then we have to wait for it to settle before we can feed him.
Date published: 2018-02-09
Rated 5 out of 5 by from SO HAPPY I TRIED THIS!! I was a hardcore enfamil momma and finally broke down and decided to give Similac a try. My baby bear has a sensitive tummy and it’s difficult to find formulas that help with spit up, constipation, fussiness, and lactose sensitivity all in the same formula which is why I went on the hunt, the variety of formula Similac offers is amazing especially this one it’s delicate enough that my baby boy has ZERO problems and I noticed a change after the first day. I did try the Pro-Sensitive as well which is great but just didn’t work for us the way this one does, I’m so happy to say I’m now a Similac mom. Thank you so much for your wonderful product!
Date published: 2018-02-06
Rated 2 out of 5 by from Not for our little guy. We tried Similac Pro-advance for our little man first, it was way too much for his newborn tummy. So we switched to Pro-sensitive, he did better on it but was still very gassy and having trouble passing it. No other real issues just very gassy, so I called his pediatrician and the nurse suggested we switch to Total Comfort. All I really wanted was to see if we could give him probiotics or something to help with digestion. With much apprehension, I made the switch and BOY was it a BAD idea!! Pros- he burped easier and had no problems passing gas Cons- he pooped at least 8 times within 24 hours and his little butt is RAW so he's been screaming in pain every time he poops, he started spitting up, his gas smelled absolutely terrible, and the formula did not seem to fill him up at all. After about 6 bottles I switched my poor dude back to Pro-sensitive. We'll take gas cramps over my baby suffering in pain any day.
Date published: 2018-01-31
Rated 5 out of 5 by from Works great for my breastfeeding baby My daughter had so much trouble both breastfeeding and taking formula in her first month. I breastfeed her 90% of the time but when I do need to give her formula, she is able to digest this one easily with no tummy aches.
Date published: 2018-01-29
Rated 4 out of 5 by from Works for sensitive tummies Great formula my son does great on it. Still have not received any coupons or samples and I signed up 2 months ago. I get plenty of enfamil and others but would love similac
Date published: 2018-01-09
Rated 1 out of 5 by from Bad experience with this product Switched my daughter to this from Gerber Good Start Soothe and was a total mistake. Doctor suggested the Pro Sensitive but I'm not sure to try again Similac. How can I get a refund?
Date published: 2018-01-08
Rated 5 out of 5 by from Night and day We were given pro advance in the hospital and our daughter did great on it for about a week then major spitting up set in. So per the pediatrician we switched to enfamil newborn which has made her super gassy and she only has a bowel movement, that she has to strain excessively for, every 2-3 days. I have a huge tub of similac pro-advance that I purchased at sams that has not been open for a month yet so I switched back to it to make sure the spitting up wasn’t just a fluke. She went right back to projectile vomiting. This morning I purchased the similac total comfort and we have had no spitting up and no gas today. I am hoping this continues into tomorrow and I am looking forward to seeing what happens with her constipation. My only complaint is the smell of this formula.
Date published: 2018-01-04
Rated 1 out of 5 by from Total disaster My 3 week old was on Pro Sensitive, but continued to struggle with gas and constipation. Our pediatrician recommended Total Comfort, so we tried it. He had about 2-3 bottles and that night he was so restless with horrible gas. He fought it so bad, and it took over 4 hours to calm him down and for him to fall asleep. We switched him back to the Pro Sensitive with the next bottle.
Date published: 2017-12-31
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