Similac Total Comfort NON‑GMO*,†

Complete nutrition for delicate tummies

If your baby is experiencing discomfort due to persistent feeding issues, Similac Total Comfort NON‑GMO may help.

Partially broken-down protein for easy digestion.

Has OptiGRO to support your baby's brain and eye development.

*Ingredients not genetically engineered.
Not for infants or children with galactosemia.

Similac Total Comfort NON-GMO formula for easy digestion.

Available In:

Similac Total Comfort NON-GMO formula for easy digestion. 1.41-lb Powder

Nutrition Information

Powder / 1.41 lb

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

Amount per serving

  • Calories:


  • Volume, mL:


  • Protein, g:


  • Fat, g:


  • Carbohydrate, g:


  • Water, g:


  • Linoleic Acid, mg:


Vitamins & Minerals

Similac Total Comfort™ NON-GMO
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Rated 4 out of 5 by from Hoping this works My DD started with Similac advance, which made her fussy and uncomfortable, then we tried the pro sensitive o dear that was worse her tummy was always growling and she squirms in pain and she was constipated, her pediatrician had to give her total comfort for a try. We still on it and hoping this changes everything, tho she has reduced the grunting and squirms but her tummy stil growls. I am not comfortable with the smell coz all her bottle smells even after washes n sterilized. Yes she has stopped fussing and more comfortable in her sleep, just still her tummy growling.
Date published: 2018-03-13
Rated 5 out of 5 by from Hope this works We started my daughter on Similac Pro sensitive due to it being suggested by the hospital when she was born. She became a very fussy, gassy, and unhappy baby. We then tried Enfamil Gentlease and she was worse. So as of today her pediatrician has put her on Total Comfort. We really hope this works!!
Date published: 2018-03-12
Rated 5 out of 5 by from Thankful We Found This Formula I went back to work when my son was 4 months old. Up until then, he had been exclusively breastfed. I had to supplement with formula since my supply took a plunge, so I tried Similac Supplementation first. (It made sense). Unfortunately, my son started having issues with sinus congestion, excessive gas, constipation and eczema shortly after starting on the formula. After a lot of research, and having strong faith in Similac, (my 11 year old daughter was a Similac baby and so was I), I tried the Total Comfort. After only a few days on this formula, my son's skin has cleared up remarkably, and his BMs are now regular and easy for him to pass. Now I don't have to fret so much about my milk supply, and what my son will eat when I am done breast feeding. Thank you Similac!
Date published: 2018-03-03
Rated 3 out of 5 by from Terrible gas pains My son was put on Similac soy at the hospital but became so constipated he was going a week at a time with no bowel movements. When he did have one he screamed in pain and strained. His doctor moved him to total comfort but now he has horrible gas pains and screams and cries until he throws up most of his bottle. His doctor tried moving him back to the soy formula but he projectile vomits on that. So she moved him back to total comfort because he is still gaining so it seemed he does not need the hypoallergenic formula. I guess we take crying and a slightly lesser amount of spit up/vomiting over constipation and exorcism vomiting. It is a shame because my oldest was a similac baby just wish we could find one that works for our youngest but we keep having to buy cans of formula and then throw most of it out. Oh and as you mix the powder if you mix it even a little to vigorously it becomes foam then we have to wait for it to settle before we can feed him.
Date published: 2018-02-09
Rated 5 out of 5 by from SO HAPPY I TRIED THIS!! I was a hardcore enfamil momma and finally broke down and decided to give Similac a try. My baby bear has a sensitive tummy and it’s difficult to find formulas that help with spit up, constipation, fussiness, and lactose sensitivity all in the same formula which is why I went on the hunt, the variety of formula Similac offers is amazing especially this one it’s delicate enough that my baby boy has ZERO problems and I noticed a change after the first day. I did try the Pro-Sensitive as well which is great but just didn’t work for us the way this one does, I’m so happy to say I’m now a Similac mom. Thank you so much for your wonderful product!
Date published: 2018-02-06
Rated 2 out of 5 by from Not for our little guy. We tried Similac Pro-advance for our little man first, it was way too much for his newborn tummy. So we switched to Pro-sensitive, he did better on it but was still very gassy and having trouble passing it. No other real issues just very gassy, so I called his pediatrician and the nurse suggested we switch to Total Comfort. All I really wanted was to see if we could give him probiotics or something to help with digestion. With much apprehension, I made the switch and BOY was it a BAD idea!! Pros- he burped easier and had no problems passing gas Cons- he pooped at least 8 times within 24 hours and his little butt is RAW so he's been screaming in pain every time he poops, he started spitting up, his gas smelled absolutely terrible, and the formula did not seem to fill him up at all. After about 6 bottles I switched my poor dude back to Pro-sensitive. We'll take gas cramps over my baby suffering in pain any day.
Date published: 2018-01-31
Rated 5 out of 5 by from Works great for my breastfeeding baby My daughter had so much trouble both breastfeeding and taking formula in her first month. I breastfeed her 90% of the time but when I do need to give her formula, she is able to digest this one easily with no tummy aches.
Date published: 2018-01-29
Rated 4 out of 5 by from Works for sensitive tummies Great formula my son does great on it. Still have not received any coupons or samples and I signed up 2 months ago. I get plenty of enfamil and others but would love similac
Date published: 2018-01-09
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